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Table 3 Variation in frequency of alleles with age from samples obtained by PCR directly from biopsies or subcultured H. pylori.

From: PCR-based genotyping of Helicobacter pylori of Gambian children and adults directly from biopsy specimens and bacterial cultures

Age (years) Total cagA+ cagA- cagA+&- Not amplified P-value
1.5-2.5 6 1(16.7) 5(83.3) 0(0) 0(0)  
9-29 54 35(64.8) 10(18.5) 8(14.8) 1(1.8)  
30-40 31 22(71.0) 2(6.5) 6(19.3) 1(3.2)  
41-59 24 15(62.5) 4(16.7) 4(16.7) 1(4.2)  
>=60 12 2(16.7) 5(41.7) 5(41.7) 0(0) 0.001
Age (years) Total s1 s2 s1 & s2 Not amplified P-value
1.5-2.5 6 1(16.7) 5(83.3) 0(0) 0(0)  
9-29 54 43(79.6) 9(16.7) 0(0) 2(3.7)  
30-40 31 27(87.1) 3(9.7) 0(0) 1(3.2)  
41-59 24 18(75.0) 5(20.8) 0(0) 1(4.2)  
>=60 12 5(41.7) 6(50.0) 1(8.3) 0(0) <0.001
Age (years) Total m1 m2 m1 & m2 Not amplified P-value
1.5-2.5 6 1(16.7) 5(83.3) 0(0) 0(0)  
9-29 54 25(46.3) 17(31.5) 10(18.5) 2(3.7)  
30-40 31 16(51.6) 8(25.8) 5(16.1) 2(6.5)  
41-59 24 12(50.0) 4(16.7) 4(16.7) 4(16.7)  
>=60 12 2(16.7) 7(58.3) 3(25.0) 0(0) 0.103
Age (years) Total iceA1 iceA2 iceA1 & 2 Not amplified P-value
1.5-2.5 6 3(50.0) 1(16.7) 2(33.3) 0(0)  
9-29 54 3(5.6) 19(35.2) 29(53.7) 3(5.6)  
30-40 31 6(19.3) 7(22.6) 15(48.4) 3(9.7)  
41-59 24 4(16.7) 10(41.7) 7(29.2) 3(12.5)  
>=60 12 2(16.7) 6(50.0) 4(33.3) 0(0) 0.065