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Table 3 Variation in frequency of alleles with age from samples obtained by PCR directly from biopsies or subcultured H. pylori.

From: PCR-based genotyping of Helicobacter pylori of Gambian children and adults directly from biopsy specimens and bacterial cultures

Age (years)

Total

cagA+

cagA-

cagA+&-

Not amplified

P-value

1.5-2.5

6

1(16.7)

5(83.3)

0(0)

0(0)

 

9-29

54

35(64.8)

10(18.5)

8(14.8)

1(1.8)

 

30-40

31

22(71.0)

2(6.5)

6(19.3)

1(3.2)

 

41-59

24

15(62.5)

4(16.7)

4(16.7)

1(4.2)

 

>=60

12

2(16.7)

5(41.7)

5(41.7)

0(0)

0.001

Age (years)

Total

s1

s2

s1 & s2

Not amplified

P-value

1.5-2.5

6

1(16.7)

5(83.3)

0(0)

0(0)

 

9-29

54

43(79.6)

9(16.7)

0(0)

2(3.7)

 

30-40

31

27(87.1)

3(9.7)

0(0)

1(3.2)

 

41-59

24

18(75.0)

5(20.8)

0(0)

1(4.2)

 

>=60

12

5(41.7)

6(50.0)

1(8.3)

0(0)

<0.001

Age (years)

Total

m1

m2

m1 & m2

Not amplified

P-value

1.5-2.5

6

1(16.7)

5(83.3)

0(0)

0(0)

 

9-29

54

25(46.3)

17(31.5)

10(18.5)

2(3.7)

 

30-40

31

16(51.6)

8(25.8)

5(16.1)

2(6.5)

 

41-59

24

12(50.0)

4(16.7)

4(16.7)

4(16.7)

 

>=60

12

2(16.7)

7(58.3)

3(25.0)

0(0)

0.103

Age (years)

Total

iceA1

iceA2

iceA1 & 2

Not amplified

P-value

1.5-2.5

6

3(50.0)

1(16.7)

2(33.3)

0(0)

 

9-29

54

3(5.6)

19(35.2)

29(53.7)

3(5.6)

 

30-40

31

6(19.3)

7(22.6)

15(48.4)

3(9.7)

 

41-59

24

4(16.7)

10(41.7)

7(29.2)

3(12.5)

 

>=60

12

2(16.7)

6(50.0)

4(33.3)

0(0)

0.065