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Figure 6 | Gut Pathogens

Figure 6

From: Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice

Figure 6

Colonic COX-2 immunohistochemistry. COX-2 immunohistochemistry was performed on representative histology slides from colonic samples of three treatment groups (panels A, B and C). As shown in panel A, Immuno-staining for COX-2 was evident primarily in the colonic epithelial cells from a mouse that was not infected with C. difficile. In the colon of a Vehicle/C.difficile/Vanco treated animal there was prominent brown COX-2 staining in colonocytes, as well as infiltrating leukocytes within the lamina propria and submucosa (panel B). Only minimal COX-2 immuno-staining (i.e., primarily in surface colonic epithelial cells) was present within the colon of a BC30/C. difficile/Vanco treated mouse (panel C).

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