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Table 2 Levels of anti-inflammatory cytokines, IL-4 and IL-10, in intranasally infected mice with C. jejuni (mean±SD)

From: Induction of cytokines in different organs after intranasal inoculation of Campylobacter jejuni in mice

Organ

Group

Day 1

Day 3

Day 5

Day 10

IL-4

IL-10

IL-4

IL-10

IL-4

IL-10

IL-4

IL-10

Spleen

Test

15277 (±6630)

314 (±32) *

22824 (±3489)

326 (±125)

40284 (±10363)*

364 (±38)

9509 (±3368)

190 (±129)

Control

23230 (±3829)

239 (±34)

16706 (±7430)

354 (±54)

21164 (±1355)

433 (±201)

18770 (±4750)

130 (±49)

Large intestine

Test

1 (±1)

2 (±0)

4 (±3)

10 (±11)

31 (±31)*

103 (±113)*

5 (±1)

12 (±3)

Control

3 (±1)

13 (±10)

6 (±5)

37 (±6)

6 (±3)

13 (±12)

8 (±2)

6 (±4)

Liver

Test

4960 (±5721)

90 (±14)

15856 (±15787)

122 (±21)

13820 (±3241)*

276 (±45)*

ND

216 (±14)

Control

20819 (±6306)

148 (±23)

5033 (±3280)

147 (±40)

6380 (±2833)

138 (±45)

ND

211 (±68)

Small intestine

Test

15 (±10)

2 (±0)

31 (±4)*

7 (±7)

19 (±10)

23 (±15)*

11 (±3)

11 (±9)

Control

23 (±11)

2 (±0)

15 (±9)

8 (±5)

23 (±11)

2 (±1)

22 (±5)

6 (±4)

Serum

Test

786 (±194)*

339 (±70)

239 (±85)

152 (±118)

435 (±70)*

48 (±31)

335 (±108)

113 (±70)

Control

323 (±29)

236 (±118)

1690 (±123)

484 (±321)

284 (±78)

304 (±157)

409 (±123)

323 (±128)

  1. * Indicates significant difference (P≤ 0.05) in values between test and control mice; ND, not done.