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Table 2 Levels of anti-inflammatory cytokines, IL-4 and IL-10, in intranasally infected mice with C. jejuni (mean±SD)

From: Induction of cytokines in different organs after intranasal inoculation of Campylobacter jejuni in mice

Organ Group Day 1 Day 3 Day 5 Day 10
IL-4 IL-10 IL-4 IL-10 IL-4 IL-10 IL-4 IL-10
Spleen Test 15277 (±6630) 314 (±32) * 22824 (±3489) 326 (±125) 40284 (±10363)* 364 (±38) 9509 (±3368) 190 (±129)
Control 23230 (±3829) 239 (±34) 16706 (±7430) 354 (±54) 21164 (±1355) 433 (±201) 18770 (±4750) 130 (±49)
Large intestine Test 1 (±1) 2 (±0) 4 (±3) 10 (±11) 31 (±31)* 103 (±113)* 5 (±1) 12 (±3)
Control 3 (±1) 13 (±10) 6 (±5) 37 (±6) 6 (±3) 13 (±12) 8 (±2) 6 (±4)
Liver Test 4960 (±5721) 90 (±14) 15856 (±15787) 122 (±21) 13820 (±3241)* 276 (±45)* ND 216 (±14)
Control 20819 (±6306) 148 (±23) 5033 (±3280) 147 (±40) 6380 (±2833) 138 (±45) ND 211 (±68)
Small intestine Test 15 (±10) 2 (±0) 31 (±4)* 7 (±7) 19 (±10) 23 (±15)* 11 (±3) 11 (±9)
Control 23 (±11) 2 (±0) 15 (±9) 8 (±5) 23 (±11) 2 (±1) 22 (±5) 6 (±4)
Serum Test 786 (±194)* 339 (±70) 239 (±85) 152 (±118) 435 (±70)* 48 (±31) 335 (±108) 113 (±70)
Control 323 (±29) 236 (±118) 1690 (±123) 484 (±321) 284 (±78) 304 (±157) 409 (±123) 323 (±128)
  1. * Indicates significant difference (P≤ 0.05) in values between test and control mice; ND, not done.