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Table 3 Salmonella genes whose relative expression was decreased by indole

From: Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses

STM no.

Gene

Function

Effect of indole on gene expression (fold change)

Concentration of indole (mM)

1

4

STM0701

speF

Ornithine decarboxylase isozyme, inducible

0.35

0.038

STM0964

dmsA

Anaerobic dimethyl sulfoxide reductase, subunit A

0.12

0.063

STM0965

dmsB

Anaerobic dimethyl sulfoxide reductase, subunit B

0.13

0.025

STM1092

orfX

Putative cytoplasmic protein

0.082

0.031

STM1171

flgN

Flagellar biosynthesis: belived to be export chaperone for FlgK and FlgL

0.27

0.082

STM1183

flgK

Flagellar biosynthesis, hook-filament junction protein 1

0.19

0.031

STM1184

flgL

Flagellar biosynthesis; hook-filament junction protein

0.18

0.044

STM1626

trg

Methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor

0.15

0.054

STM1732

ompW

Outer membrane protein W; colicin S4 receptor; putative transporter

0.29

0.047

STM1764

narG

Nitrate reductase 1, alpha subunit

0.095

0.041

STM1765

narK

MFS superfamily, nitrite extrusion protein

0.058

0.047

STM1917

cheB

Methyl esterase, response regulator for chemotaxis (cheA sensor)

0.27

0.067

STM1918

cheR

Glutamate methyltransferase, response regulator for chemotaxis

0.14

0.0078

STM1919

cheM

Methyl accepting chemotaxis protein II, aspartate sensor-receptor

0.18

0.018

STM1921

cheA

Sensory histitine protein kinase, transduces signal between chemo- signal receptors and CheB and CheY

0.18

0.029

STM1922

motB

Enables flagellar motor rotation, linking torque machinery to cell wall

0.15

0.021

STM1923

motA

Proton conductor component of motor, torque generator

0.20

0.036

STM1960

fliD

Flagellar biosynthesis; filament capping protein; enables filament assembly

0.31

0.011

STM1961

fliS

Flagellar biosynthesis; repressor of class 3a and 3b operons (RflA activity)

0.31

0.019

STM1962

fliT

Flagellar biosynthesis; possible export chaperone for FliD

0.25

0.038

STM2256

napB

Periplasmic nitrate reductase, small subunit, cytochrome C550, in complex with NapA

0.23

0.082

STM2257

napH

Ferredoxin-type protein: electron transfer

0.12

0.067

STM2258

napG

Ferredoxin-type protein: electron transfer

0.077

0.027

STM2259

napA

Periplasmic nitrate reductase, large subunit, in complex with NapB

0.072

0.033

STM2260

napD

Periplasmic nitrate reductase

0.063

0.0078

STM2261

napF

Ferredoxin-type protein: electron transfer

0.044

0.024

STM2872

prgJ

Cell invasion protein; cytoplasmic

0.22

0.10

STM2873

prgI

Cell invasion protein; cytoplasmic

0.18

0.041

STM2874

prgH

Cell invasion protein

0.082

0.0078

STM2885

sipB

Cell invasion protein

0.33

0.11

STM2897

invE

Invasion protein

0.25

0.038

STM2899

invF

Invasion protein

0.12

0.095

STM3127

 

Putative cytoplasmic protein

0.29

0.058

STM3128

 

Putative oxidoreductase

0.14

0.036

STM3129

 

Putative NAD-dependent aldehyde dehydrogenase

0.14

0.047

STM3149

hybA

Function unknown, intitally thought to be hydrogenase-2 small subunit which now identified as hybO

0.25

0.025

STM3216

 

Putative methyl-accepting chemotaxis protein

0.16

0.038

STM3217

aer

Aerotaxis sensor receptor, senses cellular redox state or proton motive force

0.13

0.047

STM3242

tdcD

Propionate kinase/acetate kinase II, anaerobic

0.14

0.029

STM3243

tdcC

HAAAP family, L-threonine/L-serine permease, anaerobically inducible

0.082

0.044

STM3244

tdcB

Threonine dehydratase, catabolic

0.063

0.029

STM3245

tdcA

Transcriptional activator of tdc operon (LysR family)

0.18

0.095

STM3577

tcp

Methyl-accepting transmembrane citrate/phenol chemoreceptor

0.13

0.041

STM3626

dppF

ABC superfamily (atp_bind), dipeptide transport protein

0.31

0.036

STM3628

dppC

ABC superfamily (membrane), dipeptide transport protein 2

0.33

0.088

STM4258

 

Putative methyl-accepting chemotaxis protein

0.08

0.088

STM4300

fumB

Fumarase B (fumarate hydratase class I), anaerobic isozyme

0.19

0.088

STM4305

 

Putative anaerobic dimethyl sulfoxide reductase, subunit A

0.14

0.082

STM4306

 

Putative anaerobic dimethyl sulfoxide reductase, subunit B

0.11

0.058

STM4452

nrdD

Anaerobic ribonucleoside-triphosphate reductase

0.047

0.095

STM4465

 

Putative ornithine carbamoyltransferase

0.19

0.10

STM4466

 

Putative carbamate kinase

0.19

0.10

STM4467

 

Putative arginine deiminase

0.082

0.019