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Table 3 Most important associations between biochemical parameters, gut microbiota and BMI SDS represented by regression coefficient β (p value)

From: Differences in gut microbiota composition between obese and lean children: a cross-sectional study

  Biochemical markers
  Leukocytes Glucose Insulin HDL-C TG TC ALT AST hs-CRP
  (%) (mg/dl) (μU/ml) (mg/dl) (mg/dl) (mg/dl) (U/l) (U/l) (mg/l)
Quantitative plating          
Bacteroides fragilis group   −1.469   −1.677   −6.926    
  (0.237)   (0.099)   (0.497)    
Bifidobacterium spp.   0.830     5.673 −1.619 −0.124  
  (0.631)     (0.719) (0.753) (0.969)  
Clostridium spp. −0.276 0.071 −3.725   2.322 22.353   −3.598  
(0.562) (0.967) (0.343)   (0.932) (0.181)   (0.245)  
Staphylococcus spp.     1.718 −30.933 −32.137    
    (0.414) (0.381) (0.122)    
Lactobacillus spp.    2.040       0.171
   (0.497)       (0.007)*
qPCR          
Bacteroides-Prevotella-Porphyromonas spp.     −0.668      
    (0.771)      
Bifidobacterium spp.          
Clostridium coccoides-Eubacterium rectale group 0.860 0.825   1.259   33.654 −3.686 −6.465 0.285
(0.107) (0.810)   (0.688)   (0.234) (0.518) (0.189) (0.292)
Clostridium leptum group          
Staphylococcus spp.      11.856     
     (0.481)     
Lactobacillus spp.   −1.307 1.342   17.604 −5.764   6.274 −0.004
  (0.518) (0.703)   (0.468) (0.717)   (0.139) (0.979)
BMI SDS 0.726 2.449 1.008 2.588 75.925 29.824 19.310 10.655 0.181
(0.469) (0.392) (0.900) (0.406) (0.086) (0.207) (0.072) (0.117) (0.390)
  1. Regression coefficient with 95% CI. *Significant association with p value < 0.05.