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Figure 2 | Gut Pathogens

Figure 2

From: The bioluminescent Listeria monocytogenes strain Xen32 is defective in flagella expression and highly attenuated in orally infected BALB/cJ mice

Figure 2

Lmo-Xen32 strains show reduced organ burden after oral infection of BALB/c mice compared to Lmo-EGDe strains. BALB/cJ mice (n = 8) were infected with 5 × 109 CFU Lmo-Xen32, Lmo-Xen32-mur, Lmo-EGDe-lux or Lmo-EGDe-mur-lux. At indicated time points bacterial organ loads were determined in the small intestine, mesenteric lymph nodes, liver and spleen (n = 8). 3 d.p.i (A, C) and 5 d.p.i. (B, D) indicate 3 or 5 days post infection, respectively. Graphs demonstrated mean with standard error of bacterial load in inner organs. Statistical significance between Xen32 and EGDe strains are indicated (*p < 0.05, **p < 0.01, ***p < 0.001, non-parametric Mann–Whitney-U-test).

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