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Table 4 Virulence analysis for all 26 isolates by combining results obtained from presence of virulent associated genes, phagocytosis, serum complement killing and mice lethality

From: Genotypes and virulence in serotype K2 Klebsiella pneumoniae from liver abscess and non-infectious carriers in Hong Kong, Singapore and Taiwan

Strain no. Source* MLST Phagocytosis Serum kfu Aerobactin LD50(cfu) Virulence
1 Carriage ST65 S S - - 1.2 × 105 +
2 Liver ST65 S S - + 2.2 × 106 -
3 Carriage ST65 S R - + <1.9 × 102 +++
4 Liver ST65 S R - + <1.3 × 102 +++
5 Liver ST65 R S - + <1.1 × 102 +++
6 Liver ST65 R R - + <2.1 × 102 +++
7 Liver ST65 R R - + 1.0 × 102 +++
8 Carriage ST65 R R - + <2 × 102 +++
9 Liver ST66 R R - + 1.8 × 102 +++
10 Liver ST66 R R - + 1.0 × 103 +
11 Carriage ST86 S S - + <3.7 × 102 +++
12 Liver ST86 R S - + 3.4 × 104 +
13 Liver ST86 S R - + <1.0 × 102 +++
14 Carriage ST86 S R - + 5.3 × 104 +
15 Liver ST86 R R - + 5.5 × 103 +
16 Liver ST86 R R - + 1.0 × 102 +++
17 Liver ST86 R R - + <1.0 × 102 +++
18 Carriage ST86 R R - + <1.0 × 102 +++
19 Carriage ST86 R R - + <1.0 × 102 +++
20 Carriage ST86 R R - + <1.0 × 102 +++
21 Carriage ST86 R R - + 1.0 × 103  
22 Liver ST373 R R - + <3.4 × 102 +++
23 Carriage ST374 R S + + 1.5 × 103 +
24 Carriage ST375 R R + + 2.8 × 102 +++
25 Liver ST380 R R + + <1.9 × 102 +++
26 Liver ST434 S S - + 2.6 × 104 +
  1. *All isolates were carrying rmpA. No isolate was carrying all S. Interpretation of virulence was referred to reference [2]. (+++) = hypervirulent strains with an LD50 of less than 1 × 103 colony-forming units (CFU) are more likely to induce complications in mice. (+) = virulent strains with a 50% lethal dose (LD50) between ≥1 × 103 and ≤1 × 105 CFU are less likely to induce complications in mice. (−) = non-virulent strains with an LD50 of 1 × 106 CFU of greater (do not cause complications).