Human enteroendocrine cell responses to infection with Chlamydia trachomatis: a microarray study

Table 1 Differentially transcribed host genes up or down-regulated by >3-fold at 24 h after C. trachomatis infection of CNDT-2 cells compared to non-infected

Affymetrix ID	Gene name	Gene symbol	Log2 fold change	Absolute fold change
8102800	Solute carrier family 7, (cationic amino acid transporter, y + system) member 11	SLC7A11	3,50	11,28
8154381	Chromosome 9 open reading frame 150	C9orf150	3,25	9,51
7982868	ChaC, cation transport regulator homolog 1 (E. coli)	CHAC1	2,63	6,18
7928308	DNA-damage-inducible transcript 4	DDIT4	2,41	5,33
7902290	Hystathionase (cystathionine gamma-lyase)	CTH	1,89	3,72
8178086	Heat shock 70 kDa protein 1A /// heat shock 70 kDa protein 1B	HSPA1A /// HSPA1B	-1,78	3,43
8179324
8118314
8179322
8118310
8166585	Hypothetical locus FLJ32742	FLJ32742	1,77	3,41
7920873	Small nucleolar RNA, H/ACA box 42	SNORA42	1,74	3,35
7899436	Sestrin 2	SESN2	1,66	3,17
8139737	Phosphoserine phosphatase	PSPH	1,66	3,17
8060344	Tribbles homolog 3 (Drosophila)	TRIB3	1,62	3,08
8122724	UL16 binding protein 1	ULBP1	1,61	3,06
8143341	Jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)	JHDM1D	1,61	3,06
8084219	Kelch-like 24 (Drosophila)	KLHL24	1,59	3,03

Presented genes are involved in cellular amino-acid biosynthesis, stress response, carboxylic and organic acid biosynthetic process, amine biosynthetic process. Gene clustering based on Gene Ontology identified two clusters: apoptosis and ion binding.

ISSN: 1757-4749