Bacterial phyla signature of mouse appendix and stool specimens. Bacterial phyla estimates in appendix and stool samples from Winnie and C57BL/6 mice aged 12 or 15 weeks were assessed: (A) Relative abundance estimate of phylum Actinobacteria. (B) Relative abundance estimate of phylum Bacteroidetes. (C) Relative abundance estimate of phylum Firmicutes. (D) Relative abundance estimate of phylum Proteobacteria. Bacteriodetes was significantly lesser in 15-week Winnie appendices compared to 15-week Winnie stool samples (P < 0.01). Proteobacteria was significantly increased in Winnie mice appendices (12 weeks) in contrast to stool samples (P < 0.05). Proteobacteria was increased in Winnie group appendices (15 weeks) compared to stool samples (P < 0.05). No microbiome signature differences were observed between Winnie stool samples, and between Winnie appendix samples. Error bars represent standard error of the mean. The number of samples varied from 2–5 for each group.