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Table 2 Concentration (mM) and molar ratios (%) of metabolites measured by HPLC during periods 1-4

From: Synergistic effects of Bifidobacterium thermophilum RBL67 and selected prebiotics on inhibition of Salmonella colonization in the swine proximal colon PolyFermS model

 

Acetate

Propionate

Butyrate

total SCFA

ratio (acetate:propionate:butyrate)

PERIOD 1

     

Control

94.6-2.3

45.8-1.3

22.5-0.4

162.9-1.8

58:28:14

N-15

104.2-1.0*

43.6-1.5

22.9-1.1

170.6-3.0*

61:26:13

RBL67

96.8-6.1

43.0-0.3*

25.7-1.0*

165.5-5.4

58:26:16

R-FOS

146.8-5.9*

52.1-3.3*

26.4-0.9*

225.3-1.8*

65:23:12

PERIOD 2

     

Control

92.4-3.7

48.0-2.0

20.7-0.8

161.0-5.1

57:30:13

N-15

94.0-6.9

45.2-1.1

21.9-1.8

161.1-8.2

58:28:14

RBL67

102.3-2.6*

44.3-1.3*

24.3-1.3*

170.9-5.0*

60:26:14

FOS

126.4-5.2*

58.4-1.1*

21.0-2.4

205.8-6.0*

61:28:10

R-FOS

112.2-1.0*

60.6-0.9*

29.9-1.1*

202.7-1.5*

55:30:15

PERIOD 3

     

CR

89.5-1.8

46.9-0.1

27.0-1.8

163.4-3.6

55:29:16

SAL

86.1-1.4*

50.0-2.8

22.9-5.2*

159.0-5.2

54:31:14

RBL67

101.3-3.1*

47.3-2.0

22.7-5.9*

171.3-5.9

59:28:13

GOS

122.7-4.8*

61.1-5.5*

21.6-5.0*

205.4-5.0*

60:30:10

R-GOS

117.6-2.0*

60.4-2.7*

27.1-5.9

205.1-6.0*

57:29:13

PERIOD 4

     

CR

78.7-0.8

51.4-1.0

23.2-0.4

153.3-1.4

51:34:15

SAL

90.1-1.0*

50.9-0.9

22.8-1.7

163.8-1.7*

55:31:14

R-MOS

82.7-3.2*

64.1-1.5*

22.8-2.9

169.3-1.0*

49:38:13

R-FOS

114.6-7.6*

65.0-1.3*

24.7-0.6*

204.3-6.0*

56:32:12

R-GOS

118.5-1.1*

68.2-3.0*

20.1-0.3*

206.8-2.9*

57:33:10

  1. *Means significantly different (P?<?0.05) from CR within a metabolite and period using the Kruskal-Wallis pairwise comparison.
  2. Reported are mean values (days 24 of N-15 challenge periods)-SD and ratios are given as percentage of total SCFA (acetate, propionate, butyrate).
  3. N-15: S. Typhimurium N-15 without pro- or prebiotic; RBL67: B. thermophilum RBL67 alone; FOS: FOS alone; R-FOS: B. thermophilum RBL67?+?FOS; GOS: GOS alone; R-GOS: B. thermophilum RBL67?+?GOS; R-MOS: B. thermophilum RBL67?+?MOS.