Table 3 Spearman’s rank correlation coefficients between specified OTUs and rotavirus-specific IFN-γ+CD8+ or IFN-γ+CD4+ T cells among all Gn pigs
From: Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs
OTU | Tissue | T cell type | ρ | p value | adj. p value | |
|---|---|---|---|---|---|---|
Positive correlations | ||||||
PCD0 | Collinsella | Ileum | CD8+ | 0.91 | <0.01 | 0.001 |
Collinsella | Blood | CD8+ | 0.83 | <0.01 | 0.016 | |
Collinsella | Blood | CD4+ | 0.89 | <0.01 | 0.002 | |
PCD7 | Clostridiales (unclassified) | Ileum | CD8+ | 0.89 | <0.01 | 0.002 |
Mycoplasmataceae (unclassified) | Ileum | CD8+ | 0.80 | 0.01 | 0.021 | |
Negative correlations | ||||||
PCD0 | Clostridium | Ileum | CD8+ | −0.90 | <0.01 | 0.002 |
Anaerococcus | Ileum | CD8+ | −0.88 | <0.01 | 0.002 | |
Propionibacterium | Blood | CD8+ | −0.88 | <0.01 | 0.002 | |
Bacillales (unclassified) | Blood | CD8+ | −0.87 | <0.01 | 0.003 | |
Blautia | Blood | CD8+ | −0.81 | <0.01 | 0.009 | |
Clostridium | Ileum | CD4+ | −0.83 | <0.01 | 0.013 | |
Anaerococcus | Ileum | CD4+ | −0.86 | <0.01 | 0.006 | |
Clostridiales (unclassified) | Blood | CD4+ | −0.89 | <0.01 | <0.01 | |
Clostridiales (unclassified) | Blood | CD4+ | −0.82 | <0.01 | 0.014 | |
PCD7 | Anaerococcus | Ileum | CD8+ | −0.84 | <0.01 | 0.010 |
Anaerococcus | Spleen | CD8+ | −0.83 | <0.01 | 0.016 | |
Anaerococcus | Spleen | CD4+ | −0.87 | <0.01 | 0.005 | |
Staphylococcus | Spleen | CD4+ | −0.81 | <0.01 | 0.020 | |