Table 4 Characterization of HGM samples used for oral inoculation of Gn pigs
From: Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs
| Â | SV14 (healthy gut) | PM25 (unhealthy gut) |
|---|---|---|
Enteropathy score | 4 | 11 |
Myeloperoxidase | 0.37 μg/ml | 2.08 μg/ml |
α-1-antitrypsin | 22.9 μg/ml | 141.4 μg/ml |
Neopterin | 74.7Â nmol/l | 412.4Â nmol/l |
Calprotectin | 148.5 μg/g | 220.6 μg/g |
Pre-vaccination IgA titer | 1:20 | 1:50 |
Post-vaccination IgA titer | 1:3200 | 1:100 |
Fold increase in IgA titer | 160 | 2 |
Phylogenetic diversity | 7.8 | 5.7 |
Shannon Index | 4 | 3.3 |
Observed species | 107.4 | 67.3 |