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Table 2 Summary of protein coding sequences annotated as belonging to the “Virulence, Disease, and Defense” subsystem in the SEED database

From: Genome sequence of a commensal bacterium, Enterococcus faecalis CBA7120, isolated from a Korean fecal sample

Subsystem Role Location
Streptococcus pyogenes recombinatorial zone Chaperonin (heat shock protein 33) Contig 3
Colicin V and bacteriocin production cluster Dihydrofolate synthase Contig 3
Folylpolyglutamate synthase Contig 3
Amidophosphoribosyltransferase Contig 3
Acetyl-coenzyme A carboxyl transferase beta chain Contig 3
Colicin V production protein Contig 3
tRNA pseudouridine synthase A Contig 3
Copper homeostasis Negative transcriptional regulator-copper transport operon Contig 3
Copper-translocating P-type ATPase Contig 3
Copper chaperone Contig 3
Cobalt-zinc-cadmium resistance DNA-binding heavy metal response regulator Contig 3
Cobalt-zinc-cadmium resistance protein Contig 3
Transcriptional regulator, MerR family Contig 3
Resistance to fluoroquinolones DNA gyrase subunit B Contig 3
DNA gyrase subunit A Contig 3
Topoisomerase IV subunit B Contig 3
Topoisomerase IV subunit A Contig 3
Copper homeostasis: copper tolerance Cytoplasmic copper homeostasis protein CutC Contig 3
Magnesium and cobalt efflux protein CorC Contig 3
Beta-lactamase Beta-lactamase class C and other penicillin-binding proteins Contig 3
Beta-lactamase Contig 3
Metal-dependent hydrolases of the beta-lactamase superfamily I Contig 3
Cadmium resistance Cadmium resistance protein Contig 1
Cadmium efflux system accessory protein Contig 1
Multidrug resistance efflux pumps Multidrug resistance efflux pump PmrA Contig 3
Multi antimicrobial extrusion protein [Na(+)/drug antiporter], MATE family of MDR efflux pumps Contig 3
Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog Contig 3
Multidrug-efflux transporter, major facilitator superfamily (MFS) Contig 3