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Table 1 List of 16 virulence factors screened in present study, categorized based on their association with Escherichia coli pathotypes

From: Antibiotic resistance, serogroups, virulence genes, and phylogenetic groups of Escherichia coli isolated from yaks with diarrhea in Qinghai Plateau, China

Pathotype

Virulence factor categories

Function

Adhesins

Capsule synthesis

Toxins

ExPEC

sfa

  

S fimbriae (sialic acid-specific)

  

cnf1

Cytotoxic necrotizing factor 1

papC

  

Pilus associated with pyelonephritis (P fimbriae)

  

hlyA

α-Hemolysin

 

rfc

 

Lipopolysaccharide synthesis

sepA

  

Secreted serine protease of the auto-transporter family

EAEC

etrA

  

Component of ETT2 type III secretion system

EIEC

aer

  

Aerobatin

ETEC

faeG

  

F4 fimbrial adhesion

fasAb

  

Fimbrial adhesion

  

eltAb

Heat-labile enterotoxin

  

estAb

Heat-stable enterotoxin

EPEC

eaeAa

  

Intimin/attaching and effacing

  

exhAa, b

Enterohemolysin

EHEC

eaeAa

  

Intimin/attaching and effacing

  

stx1b

stx2b

Shiga-toxin-I

Shiga-toxin-II

   

exhAa,b

Enterohemolysin

  1. aIndicates genes shared by more than one E. coli pathotype
  2. bIndicates none of the isolates were positive for these genes