Pathotype | Virulence factor categories | Function | ||
---|---|---|---|---|
Adhesins | Capsule synthesis | Toxins | ||
ExPEC | sfa | Â | Â | S fimbriae (sialic acid-specific) |
 |  | cnf1 | Cytotoxic necrotizing factor 1 | |
papC | Â | Â | Pilus associated with pyelonephritis (P fimbriae) | |
 |  | hlyA | α-Hemolysin | |
 | rfc |  | Lipopolysaccharide synthesis | |
sepA | Â | Â | Secreted serine protease of the auto-transporter family | |
EAEC | etrA | Â | Â | Component of ETT2 type III secretion system |
EIEC | aer | Â | Â | Aerobatin |
ETEC | faeG | Â | Â | F4 fimbrial adhesion |
fasAb | Â | Â | Fimbrial adhesion | |
 |  | eltAb | Heat-labile enterotoxin | |
 |  | estAb | Heat-stable enterotoxin | |
EPEC | eaeAa | Â | Â | Intimin/attaching and effacing |
 |  | exhAa, b | Enterohemolysin | |
EHEC | eaeAa | Â | Â | Intimin/attaching and effacing |
 |  | stx1b stx2b | Shiga-toxin-I Shiga-toxin-II | |
 |  |  | exhAa,b | Enterohemolysin |