Skip to main content

Table 4 Laboratory diagnostic findings during the course of infection in blood

From: Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7

   Negative E. coli O104:H4 E. coli O157:H7
Median (min–max); number of animal examined Median (min–max); number of animal examined Median (min–max); number of animal examined
Time range: reference range T1 T2 T3 T1 T2 T3 T1 T2 T3
Red blood count
 Haematocrit L/l 0.21–0.37 0.29 (0.24–0.34); 3 0.24 (0.19–0.27); 3 (0.24–0.29); 2 0.25 (0.19–0.35); 6 0.23 (0.21–0.29); 6 0.26 (0.18–0.33); 5 0.22 (0.14–0.31); 4 0.26 (0.23–0.33); 3 0.3; 1
 Haemoglobin g/l 75.0–138.9 95.0 (78.0–112.0); 3 95.9 (79.3–124.0); 3 (72.5–93.8); 2 81.5 (64.0–121.0); 6 87.3 (69.9–116.7); 6 83.2 (60.7–116.3); 5 72.5 (49.0–106.0); 4 78.8 (65.1–97.9); 3 96.8; 1
 Erythrocytes × 1012/l 3.47–6.65 4.02 (3.41–5.10); 3 3.98 (2.69–4.43); 3 (4.29–4.98); 2 3.64 (2.70–5.21); 6 3.79 (3.17–4.55); 6 4.67 (2.61–5.91); 5 3.17 (2.14–4.24); 4 4.86 (3.53–5.92); 3 5.32; 1
 Plateles × 109/l 282–946 62 (21–107); 3 638 (543–910); 3 (571–849); 2 80 (10–229); 6 549 (358–972); 6 925 (580–1180); 5 202 (31–266); 4 723 (215–998); 3 971; 1
 Normoblasts × 1012/l   0.09 (0.08–0.13); 3 0.08 (0.06–0.11); 3 (0.00–0.04); 2 0.06 (0.03–0.22); 6 0.05 (0.00–0.15); 6 0.22 (0.00–0.59); 5 0.09 (0.02–0.35); 4 0.33 (0.17–0.38); 3 0.93; 1
Blood chemistry
 Creatinin µmol/l 38–142 95 (84–99); 3 63 (57–67); 3 (51–55); 2 86.5 (55–100); 6 57 (53–73); 6 68 (55–78); 5 103 (86–106); 3 63 (52–72); 4 87; 1
 GLDH U/l 0–11.5 1.0 (0.5–2.0); 3 (0.6–1.4); 2 n.a. 1.3 (0.6–2.1); 5 0.9 (0.1–2.1); 6 0.6 (0.5–2.0); 3 0.7 (0.3–0.9); 3 0.6 (0.2–1.0); 4 0.5; 1
 LDH U/l 409–1549 2013 (1986–2830); 3 1105 (901–1445); 3 (830–1061); 2 1893 (1150–2072); 6 1309 (909–1767); 6 806 (711–1255); 5 1301 (1185–1388); 3 710 (538–804); 4 824; 1
 CK U/l 43–3343 598 (509–850); 3 98 (93–144); 3 (85–195); 2 461 (292–1515); 6 194 (66–296); 6 91 (67–288); 5 303 (241–331); 3 87 (37–111); 4 96; 1
 ASAT U/l 13.7–122.8 36 (36–55); 3 11 (11–22); 3 (12–20); 2 25 (20–36); 5 20 (9–29); 6 14 (11–15); 5 19 (17–26); 3 9 (7–14); 4 11; 1
 Plasma protein g/l 36.65–71.71 19.9 (19.5–22.9); 3 24.8 (23.9–27.8); 3 (27.0–28.5); 2 23.9 (20.9–29.5); 5 28.8 (23.3–31.5); 6 31.2 (27.2–33.1); 5 22.7 (21.9–27.4); 3 30.1 (27.5–30.7); 4 31.4; 1
 Sodium mmol/l 136.0–151.0 130.9 (129.0–132.5); 3 132.6 (130.6–133.4); 3 (129.6–134.5); 2 130.8 (125.8–138.7); 6 133.7 (133.0–137.1); 6 131.7 (130.1–135.2); 5 132.0 (129.9–134.4); 3 132.3 (129.1–135.8); 4 129.5; 1
 Potassium mmol/l 3.78–6.92 4.46 (3.32–4.75); 3 6.59 (5.74–7.60); 3 (5.23–7.04); 2 4.66 (3.99–6.22); 6 5.75 (4.96–6.89); 6 5.79 (5.15–6.12); 5 4.65 (4.44–5.50); 3 5.26 (4.85–5.80); 4 4.97; 1
Acute phase proteins
 Haptoglobin mg/ml   (0.03–0.05); 2 0.02 (0.02–0.54); 3 (0.01–0.02); 2 0.04 (0.04–0.06); 3 0.39 (0.04–0.91); 6 0.27 (0.02–1.13); 5 (0.02–0.02); 2 2.62 (2.20–3.00); 4 1.27; 1
 CRP mg/l   (<0.05–0.8); 3 3.0 (0.7–13.3); 3 (1.2–3.4); 2 0.7 (<0.05–7.3); 5 7.5 (1.3–203.2); 6 11.0 (<0.05–40.9); 5 (<0.05–1.7); 3 30.0 (9.5–220.1); 4 0.7; 1
 LBP mg/l   2.00 (1.00–6.50); 3 2.10 (1.20–4.00); 3 (2.1–4.9); 2 2.80 (0.80–5.10); 5 4.25 (1.70–9.60); 6 4.7 (1.1–8.8); 5 1.20 (1.20–1.30); 3 5.05 (1.20–9.00); 4 7;1
  1. GLDH glutamate dehydrogenase, LDH lactate dehydrogenase, CK creatine kinase, ASAT aspartate transaminase, CRP C-reactive protein, LBP lipopolysaccharide binding protein, n.a. not assessed. T1 timerange 1, preinfectionem, T2 timerange 2, day 4-day 6 p.i., T3 timerange, day 7-day 12 p.i.