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Table 3 Operon prediction

From: Outer membrane phospholipase A’s roles in Helicobacter pylori acid adaptation

Species

Representative strain

Host

Classification

Upstream

Downstream

H. acinonychis

Sheeba

Cheetah

Gastric

AmCI and AmCII

dnaN, gyrB, 2 hypothetical genes

H. cetorum

MIT 99-5656

Dolphin

Gastric

AmCI* and AmCII

dnaN, gyrB

H. pylori

ATCC 43504

Human

Gastric

AmCI and AmCII

dnaN, gyrB, 2 hypothetical genes

H. bizzozeronii

CIII-1

Human

Gastric

AmCI and AmCII

No

H. himalayensis

YS1

Marmota himalayana

Gastric

No

No

H. suis

HS5

Swine

Gastric

AmCI and AmCII

No

H. felis

ATCC 49179

Cat

Gastric

AmCI and AmCII

No

H. mustelae

12198

Ferret

Gastric

No

No

H. heilmannii

ASB1.4

Cat

Gastric

AmCI* and AmCII

No

H. bilis

ATCC 43879

Human

Enterohepatic

No

No

H. canadensis

MIT 98-5491

Human

Enterohepatic

No

No

H. canis

NCTC 12740

Human

Enterohepatic

No

pseH

H. cinaedi

CCUG 18818 = ATCC BAA-847

Human

Enterohepatic

No

metE

H. fennelliae

MRY 12-0050

Human

Enterohepatic

Hypothetical

SAM-dependent MTase genes

H. hepaticus

ATCC 51449

Mouse

Enterohepatic

No

metE, and gene encoding NADPH

H. muridarum

ST-1

Rat

Enterohepatic

No

ABC transporter gene

H. pullorum

MIT 98-5489

Human

Enterohepatic

No

No

H. rodentium

ATCC 700285

Mouse

Enterohepatic

No

No

H. trogontum

ATCC 700114

Rat

Enterohepatic

No

No

H. typhlonicus

MIT 97-6810

Mouse

Enterohepatic

No

No

H. winghamensis

ATCC BAA-430

Human

Enterohepatic

No

No

  1. Operon prediction comparing gastric and enterohepatic genes upstream/downstream from pldA. Helicobacter species. Operons are predicted by Fgenesb software (Softberry Inc., Mount Kisco, NY, US). COG0377 corresponds to the “Na+-dependent transporters (channels) of the SNF family” (this includes AmCI and AmCII). The COG0377 are phase variable genes
  2. * Truncated proteins