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Fig. 2 | Gut Pathogens

Fig. 2

From: 1,25(OH)2D3 deficiency-induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model

Fig. 2

1,25(OH)2D3 deficiency alters the composition of the gut microbiota in the Cyp27b1/ mice. a Abundance distribution of TOP 10 bacterial taxa for 8–10-month wild type and Cyp27b1/ mice at class level. N = 5. b Student’s t test analysis revealed the significant changed bacteria in species including Akkermansia muciniphila (A. muciniphila), Bacteroides-acidifaciens, Bacteroides plebeius, Bacteroides uniformis, Roseburia inulinivorans, and Solitalea canadensis in Cyp27b1/ mice. c Relative abundance of A. muciniphila in feces of 8–10-month wild type and Cyp27b1/ mice. d Gas chromatography was performed to measure the concentration of butyrate in feces from 8 to 10-month wild type and Cyp27b1/ mice. *P < 0.05, **P < 0.01. WT: wild type, KO: Cyp27b1/

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