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Table 2 Gut microbial richness and diversity associated with chemotherapy-induced diarrhea of the CapeOX regimen in CRC

From: Gut microbiome associated with chemotherapy-induced diarrhea from the CapeOX regimen as adjuvant chemotherapy in resected stage III colorectal cancer

Group n Coverage OTU Ace Chao Shannon Simpson
Experimental group 4 0.9994 ± 0.0008 119.75 ± 53.44 159.50 ± 100.09 150.75 ± 77.58 2.21 ± 0.47 0.21 ± 0.08
Control group 13 0.9985 ± 0.0012 273.38 ± 93.68 336.31 ± 117.73 332.46 ± 113.34 3.36 ± 0.59 0.09 ± 0.07
t value − 3.08 − 2.70 − 2.97 − 3.54 2.30
p value 0.008 0.016 0.010 0.003 0.009
  1. Mothur software (http://www.mothur.org/wiki/Main_Page) was used to analyze the microbial diversity. Operational taxonomic units (OTU), as the artificial classification unit, was used to estimate the number of species in each sample, and the similarity threshold was 97%. The alpha diversity analysis was shown in Additional file 1