Fig. 6

Pathologic changes in the rats bladders infected with UPEC. a Control uninfected bladder; b bladder infected by E. coli coded 13β (hly⁺ cnf 1⁻ clbA⁻ clbQ⁻); c bladder infected by E. coli isolate coded 67 (hly⁻ cnf 1⁻ clbA⁻ clbQ⁻); d bladder infected by E. coli coded 6β (hly⁺ cnf 1⁺ clbA⁺ clbQ⁺); (e, f): bladder infected by E. coli coded 70β (hly⁺ cnf 1⁺ clbA⁺ clbQ⁺). p, Lamina propria; e, edema; ds, desquamated epithelium; hp, hyperplastic changes. Continuous arrows indicate normal transitional epithelium (a); inflammatory cell infiltration (b); vacuolar degeneration and inflammatory cell infiltration (c); necrosis (d); degenerative necrosis (e). The detailed description of the pathologic changes is mentioned in Table 3