Fig. 1

Sequence alignment of PGDH from P. aeruginosa, E. coli, and human. The number denotes the position of the amino acid residue in the sequence of E. coli PGDH from a previous report by Tobey and Grant [23]. The black boxes indicate identical residues, and the gray boxes show amino acid similarity. Blue dots show the Pro-336-Gly-337 at the connecting region between the ACT domain and the substrate-binding domain in P. aeruginosa PGDH [7, 8]. PA refers to P. aeruginosa, EC to E. coli, and HS to human