Table 1 Interested immune-related DEGs with their annotated identities, primary annotation, secondary annotation and log2 fold changes

Pathogen-induced interactive response genes

 Unigene 10589

Mucin

KEGG: K10955 intestinal mucin-2

3.940*

1.457*

− 0.0589

 CL1511.Contig2

Chitinase

KEGG: K01183 chitinase

9.723*

1.018

− 0.963

 Unigene 6305

Chitin deacetylase

NR: ABW74152.1| chitin deacetylase 9 [Tribolium castaneum]

9.862*

− 7.539*

6.792*

PAMPs and DAMPs genes

 Unigene 5450

C-type Lectin

NR: AAZ29608.1|/1.17917e-129/C-type lectin [Penaeus monodon]

1.766*

1.841*

2.097*

 Unigene 274

Galectin

KEGG: GB18324; galectin 2

2.354*

0.126

2.072*

 Unigene 17462

HMGB1

NR: ADQ43366.1|/3.82992e-161/HMGBa [Litopenaeus vannamei]

2.570*

0.926

2.719*

Pathway-related genes

 Unigene 21346

STAT

KEGG: K11224 signal transducer and activator of transcription 5B

2.569*

1.693*

2.655*

 Unigene 1234

Toll

NR: ABO38434.1|/0/Toll receptor [Penaeus monodon]

3.135*

− 0.939

3.170*

 Unigene 18449

IMD

NR: ACL37048.1|/2.11556e-113/IMD [Litopenaeus vannamei]

6.949*

0

5.044*

 Unigene 17197

TBK1

KEGG: K12652 TANK-binding kinase 1-binding protein

2.079*

− 0.748

0.376

AMPs genes

 Unigene 16331

ALF

NT: EF523560.1/2e-78/Penaeus monodon anti-lipopolysaccharide factor isoform 1 (ALFPm1) gene, complete cds

2.215*

3.051*

3.478*

 Unigene 19432

Penaeidin

NR: ACH70378.1 penaeidin 3 [Penaeus monodon] & ACQ66008.1 penaeidin 5 antimicrobial peptide [Penaeus monodon]

2.867*

− 0.0884

0.353

 Unigene 10242

Stylicin

NR: ABW24769.1 stylicine 2 [Litopenaeus stylirostris]

2.960*

1.749*

1.871*

proPO system genes

 Unigene 3984

Serine proteinase

NT: AY372186.1/0.0/Penaeus monodon serine proteinase mRNA, partial cds

5.672*

3.700

8.155*

 CL3265.Contig1

SERPIN

NR: AHC06147.1|/0/serpin 3 [Penaeus monodon]

0.242

1.630*

1.352*

 Unigene 3184

proPO

NR: AGI42860.1 prophenoloxidase 3 [Fenneropenaeus chinensis]

2.208*

2.395*

0.602

Antioxidation genes

 Unigene 3737

Superoxide dismutase

KEGG: K04565 superoxide dismutase, Cu–Zn family [EC:1.15.1.1]

3.826*

− 0.198

0.0722

 Unigene 6270

Glutathione peroxidase

KEGG: K00432 glutathione peroxidase [EC:1.11.1.9]

6.298*

− 0.567

0.787

Phagocytosis-related genes

 Unigene 2116

Lysozyme

NR: ACZ63472.1i-type lysozyme-like protein 2 [Penaeus monodon]

7.762*

− 1.585

4.737*

 CL1336.Contig2

Apoptosis stimulating of P53

KEGG: K17554 apoptosis-stimulating of p53 protein 1

5.478*

− 1.663

5.482*

 Unigene 5149

Caspase

KEGG: K02186 caspase 2 [EC:3.4.22.55]

0.162

2.268*

0.874

Other immune-related genes

 Unigene 24702

Glutathione-dependent prostaglandin d Synthase

NR: AFJ11393.1|/3.09192e-104/glutathione-dependent prostaglandin d synthase [Penaeus monodon]

6.152*

− 1.170

0

 Unigene 12001

Techylectin

SwissProt: sp|Q9U8W7|TL5B_TACTR/3e-65/Techylectin-5B OS = Tachypleus tridentatus PE = 1 SV = 1

0.497

1.565*

− 3.730*

 Unigene 33847

DSCAM

KEGG: K06768 Down syndrome cell adhesion molecule-like protein 1

3.169

3.170

7.313*