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Fig. 7 | Gut Pathogens

Fig. 7

From: EV71 virus reduces Nrf2 activation to promote production of reactive oxygen species in infected cells

Fig. 7

Influence of Keap1 and Nrf2 on Akt activation and expression of pro-apoptotic proteins in EV71 infected cells. Subsequent to 24 h transfection using Keap1 and Nrf2 siRNA vector, Vero and RD cells were infected by EV71 at an MOI of 5. a, b Western blot demonstrated that Keap1 and Nrf2 silencing modulates Akt, phosphor Akt, Bax, Fas, Fas-L, Caspase-3, and cleaved Caspase-3 expression levels in EV71 infected Vero and RD cells

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