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Table 6 The distribution of CagA sequence types in different geographical regions

From: Diversity of 3′ variable region of cagA gene in Helicobacter pylori strains isolated from Chinese population

CagA type Geographical regions Total
FJ SD GX YN HL HN NM QH ZJ BJ NX TW SX XZ
East Asian type CagA ABD* 65 75 69 41 49 46 18 32 6 4 3 4 1 0 413
ABD′ 0 1 3 0 0 0 1 0 0 0 0 0 0 0 5
AB-D′ 0 0 0 0 0 0 5 0 0 0 0 0 0 0 5
AB′BD 10 3 1 24 1 0 0 0 0 0 1 0 0 1 41
AB′B′BD 2 0 0 3 0 0 0 0 0 0 0 0 0 0 5
AAABD 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
ABDABD 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
AD 0 0 0 0 1 0 1 0 0 0 0 0 0 0 2
AD′ 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
A–D′ 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1
BD 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1
AB′BB″DAB′ 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
AB′B′B′B′BD 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1
ABB″B″ 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
AB′B′B′B′B′BD 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1
D 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Total   83 80 73 69 51 46 25 32 7 4 4 4 2 1 481
western type CagA ABC 0 2 1 2 5 0 5 1 0 0 0 0 0 0 16
ABCC 0 0 1 1 0 0 2 0 0 0 0 0 0 0 4
ABCCCC 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1
AC 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1
Total   0 2 2 4 5 0 8 1 0 0 0 0 0 0 22
All CagA type total   83 82 75 73 56 46 33 33 7 4 4 4 2 1 503
  1. Isolates were from 14 regions: Fujian (FJ), Shandong (SD), Guangxi (GX), Yunnan (YN), Heilongjiang (HL), Hunan (HN), Neimenggu (NM), Qinghai (QH), Zhejiang (ZJ), Beijing (BJ), Ningxia (NX), Taiwan (TW), Shanxi (SX) and Xizang (XZ). * There was a significant difference in the presence of CagA-ABD type between different geographical regions (P < 0.01). CagA-AB′BD type was signifcantly associated with Yunnan isolates (P < 0.001). CagA-ABC type was signifcantly associated with Neimenggu isolates (P < 0.01)