Fig. 6

16 S rRNA Sequencing results of WT and Dock2^−/− gut microbiota before and after transfer to WT mice. WT mice were treated with streptomycin and then transferred with gut microbiota of WT or Dock2^−/−. Fecal samples were collected before and after gut microbiota transfer. DNA were extracted for 16 S rRNA gene sequencing analysis. A The heat map of the 30 most abundant OTUs in the sequencing results. B, C The microbiota abundance index shannon diversity analysis; D Anosim test result results. E–I Metastats test results. J, K LEfSe test results. AB represented mice before streptomycin treatment; FB-W represented WT mice before transfer, after which they were transferred with WT gut microbiota; FB-K represented for WT mice before transfer, after which they were transferred with Dock2^−/− mouse gut microbiota. FA-W represented WT mice, to which the WT mouse microbiota was transferred; FA-K represented WT mice, to which the Dock2^−/− mouse microbiota was transferred. * p < 0.05, ** p < 0.01, ns, not significantly different