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Table 2 nsSNPs and fsIndels in genes conferring resistance to CLA

From: Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai

Gene

Nucleotide change

No. among CLA-R (n = 18)

No. among CLA-S (n = 94)

P

23S rRNA

SNP

   
 

 A2143G

17 (94.44%)

2 (2.13%)

 < 0.0001

 

 A2142G

2 (11.11%)

0 (0.00%)

0.0250

 

 T2182C

6 (33.33%)

31 (32.98%)

0.9770

 

 C148T

2 (11.11%)

0 (0.00%)

0.0250

 

 T1025C

0 (0.00%)

1 (1.06%)

1.0000

 

 G1027A

14 (77.78%)

52 (55.32%)

0.0760

 

Indel

   
 

 761delAA (GAA to G)

16 (88.89%)

84 (89.36%)

1.0000

 

 762_763insT (A to AT)

5 (27.78%)

50 (53.19%)

0.0482

 

 764_765insTTT (C to CTTT)

8 (44.44%)

54 (57.45%)

0.3093

 

 1036_1037insC (A to AC)

18 (100.00%)

94 (100.00%)

1.0000

 

 1515_1516insT (C to CT)

3 (16.67%)

9 (9.57%)

0.4054

 

 No change

0 (0.00%)

13 (13.83%)

0.1232