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Table 4 nsSNPs and fsIndels in genes conferring resistance to MTZ

From: Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai

Gene

Sequence change

No. among MTZ-R (n = 73)

No. among MTZ-S (n = 39)

P

Nucleotide position

Amino acid position

rdxA

No change

No change

73 (100.00%)

39 (100.00%)

NA

frxA

SNP

 G499A

D167N

4 (5.48%)

4 (10.26%)

0.3497

 T577A

C193S

63 (86.30%)

39 (100.00%)

0.3238

 Indel

 653dupA (T to TA)

X218delinsX

70 (95.89%)

39 (100.00%)

0.5503

 No change

No change

3 (4.11%)

0 (0.00%)

0.5503

fdxB

SNP

 A112G

I38V

65 (89.04%)

39 (100.00%)

0.0488

 No change

No change

8 (10.96%)

0 (0.00%)

0.0488

  1. ins: insert, del: delete, fs: frameshift, NA: not available