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Fig. 1 | Gut Pathogens

Fig. 1

From: Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NAD+ salvage metabolic pathway

Fig. 1

Fusobacterium nucleatum is Associated with ALF activity. a The representative images of HE staining and FISH of liver in each group to assess the amount of F. nucleatum in ALF and healthy control tissues. FUS664 (green) is a FITC-conjugated F. nucleatum-specific oligonucleotide probe; EUB338 (red) is a Cy3-conjugated universal bacterial oligonucleotide probe. Magnification, 200×. b The liver histological score of liver in each group (*P < 0.05; unpaired Student’s t-test; the error bars indicate the SDs). c Liquid Chromatography–Mass Spectrometry (LC–MS) Metabolomics of liver in each group. d NAD+ level in liver tissues obtained by hepatectomy from patients. e, f Immunohistochemistry analysis on the protein levels of NAMPT and IDO in liver tissues obtained by hepatectomy from patients. *P < 0.05; unpaired Student’s t-test; The error bars indicate the SDs for triplicate samples

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Gut Pathogens

ISSN: 1757-4749