Fig. 2

A Composite plot of individual trajectories of longitudinal diversity progression in stable babies minimally-exposed to antibiotics (Group 1) shown in grey. The subject with chorioamnionitis who was excluded from all calculations of mean trajectories is shown in red. Weighted mean trajectory (thick black line)—gradient labelled in green. 95%CI for weighted mean trajectory denoted by dotted lines. B Composite graph demonstrating the three components of assessed Enterobacteriaceae relative abundance progression in stable infants minimally-exposed to antibiotics (Group 1): weighted median peak relative abundance (purple); weighted mean time to peak relative abundance (blue); weighted mean regression coefficient of fall from peak (black, with 95%CI denoted by accompanying dotted lines), with gradient shown in green; individual weighted regression coefficients from which the mean is derived (grey). As in A data from the excluded infant with chorioamnionitis (red) is not included in the calculations. CLongitudinal taxonomic profiles of the majority taxa in stable babies minimally-exposed to antibiotics (Group 1; a-m), and the excluded subject (n), highlighted in red. Horizontal red arrows indicate periods of antibiotic administration; black spots on horizontal access represent samples from which no DNA was extracted. Weeks of life is indicated on the x-axis