Table 1 Demographics of Subjects
|  | Group 1 Total (n = 13) | Excluded subject | Group 2a Total (n = 21) | Group 1 vs. Group 2a p-values | Group 2b Total (n = 16) |
|---|---|---|---|---|---|
Gestational age, mean (SD), range, weeks | 30 (0.8), 29.1–31.7 | 26.4 | 27.7 (2.3), 23.6–31.3 | 0.002* | 28.3 (2.2), 24.9–31.3 |
Birthweight, mean (SD), range, grams | 1347 (215), 1020–1780 | 1050 | 957 (294), 600–1835 | 0.0002* | 982 (316), 600–1835 |
Gender, n’/n | 7/13 (54%) Male | Female | 12/21 (57%) Male | 0.85 | 9/16 (56%) Male |
Plurality of pregnancy, n’/n | 5/13 (38%) singletons 7/13 (54%) twins (inc. two pairs) 1/13 (8%) triplet | Singleton | 17/21 (81%) Singletons 2/21 (10%) Twins 2/21 (10%) Triplets | N/A | 13/16 (81%) Singletons 2/16 (13%) Triplets 1/16 (6%) Twins |
History of abnormal Dopplers, n’/n | 5/13 (38%) | No | 3/21 (14%) | 0.11 | 3/16 (19%) |
Small for gestational age n’/n | 1/13 (8%) | No | 6/21 (29%) | 0.14 | 6/16 (38%) |
Prolonged rupture of membranes prior to delivery, n’/n | 2/13 (15%) | Yes | 7/21 (33%) | 0.25 | 4/16 (25%) |
Antenatal steroids completed > 24 h prior to delivery, n’/n | 9/13 (69%) | Yes | 14/21 (67%) | 0.88 | 11/16 (69%) |
Associated diagnosis of chorioamnionitis, n’/n | 0/13 (0%) | Yes | 8/21 (38%) | 0.01* | 5/16 (31%) |
Maternal peripartum antibiotic use, n’/n | 4/13 (31%) | Yes | 4/21 (19%) | 0.43 | 4/16 (25%) |
Location of delivery, n’/n | 13/13 (100%) Inborn | Inborn | 20/21 (95%) inborn | 1.0 | 16/16 (100%) inborn |
Primary cause of preterm birth, n’/n | 5/13 (38%) Pregnancy-induced hypertension 4/13 (31%) Poor fetal growth 2/13 (15%) PPROM 1/13 (8%) APH 1/13 (8%) Poor fetal growth in sibling | PPROM | 6/21 (29%) PPROM 5/21 (24%) Preterm labour without PPROM 4/21 (19%) Pregnancy-induced hypertension 2/21 (10%) Poor fetal growth 2/21 (10%) Poor fetal growth in sibling 1/21 (5%) APH 1/21 (5%) Decreased fetal movements | N/A | 4/16 (25%) Preterm labour without PPROM 4/16 (25%) Pregnancy-induced hypertension 3/16 (19%) PPROM 2/16 (13%) Poor fetal growth 1/16 (6%) Poor fetal growth in sibling 1/16 (6%) APH 1/16 (6%) Decreased fetal movements |
Apgar score at 5 min, median, range | 9, 6–10 | 6 | 9, 2–10 | 0.08 | 9, 2–10 |
Worst BE within first hour, median, range | − 4.3, − 11.2 to − 2.2 | − 3.5 | − 4.7, − 17.3 to − 1 | 0.73 | − 4.6, − 9 to − 1 |
Temperature on admission, mean, range, °C | 36.5, 35–38.3 | 37.1 | 36.8, 36–37.8 | 0.52 | 36.8, 36–37.8 |
Mode of delivery, n’/n | 13/13 (100%) Operative | Vaginal | 13/21 (62%) Operative | 0.01* | 11/16 (69%) Operative |