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Fig. 7 | Gut Pathogens

Fig. 7

From: Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19

Fig. 7

Relative abundance of metabolic pathways in response to different treatment regimes used for the treatment of COVID-19 in a cohort of Indian patients

(A-C) Pheatmap of bacterial gene functional prediction using the latest PICRUSt2 algorithm from the faecal samples of patients at (A) T1(Before CPT) and T2 (After CPT) time point respectively. 9 metabolic pathways were differentially abundant between the two groups. (p-value < 0.05, Mann Whitney U test). (B) 13 metabolic pathways were differentially abundant betweensevere COVID-19patients (n = 14) at T1 time point (Before antibiotics &antivirals) and T2 time point (After antibiotics & antivirals) therapy. (p-value < 0.05, Mann Whitney U test). (C) 12 metabolic pathways were differentially abundant betweenpatients given antibiotic& antiviral therapy (n = 14) and the ones with antibiotic & antiviral and convalescent plasma therapy (n = 13) at T2 time point. (p-value < 0.05, Mann Whitney U test)

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Gut Pathogens

ISSN: 1757-4749