Fig. 5
From: Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis
Metabolomics analysis of fecal metabolites between PMO and non-PMO patients. (A) Unsupervised principal component analysis (PCA) score plot demonstrating clear separation between fecal metabolomic profiles of PMO and non-PMO women based on all shared metabolites. PCA was calculated using MetaboAnalyst metabolomics analysis suite and ANOVA followed by Tukey’s multiple comparisons test using PRISM. (B) Scatter diagram demonstrating differential abundance of negative ion patterns (left) and positive ion patterns (right) of metabolomics between PMO and non-PMO patients. (C) Box plot demonstrating differential metabolite-related signaling pathways (top25) between PMO and non-PMO patients. PMO, postmenopausal osteoporosis; non-PMO, non-postmenopausal osteoporosis