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Fig. 1 | Gut Pathogens

Fig. 1

From: Single-cell RNA sequencing reveals the mediatory role of cancer-associated fibroblast PTN in hepatitis B virus cirrhosis-HCC progression

Fig. 1

The subclass of cancer-associated fibroblast cells was obtained through analysis of HCC cell subset based on single-cell transcriptome data. (A) Cells were clustered into various types using the two-dimensional UMAP projection, each color represents the annotated phenotype of each types, (B) UMAP showing the categorization of 12 cell types into six cell subsets, including subset 2 and 8 which were designated as fibroblasts. (C) Heatmap showing 10% of marker genes with significant differences among 6 subsets. (D) The subdivision of cancer-associated fibroblast cells. (left) The UMAP showed the clustering results of fibroblast cells (3 subclasses, namely CAF0-2), and (right) the results of the notes of 3 fibroblast cells. (E) Dot plot showing expression level of marker genes in the 3 subclasses of fibroblast cells. (F) The trajectory analysis of six cell subsets. (G) The pseudotime analysis of six cell subsets

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Gut Pathogens

ISSN: 1757-4749