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Fig. 3 | Gut Pathogens

Fig. 3

From: TRIM32 reduced the recruitment of innate immune cells and the killing capacity of Listeria monocytogenes by inhibiting secretion of chemokines

Fig. 3

Trim32 deficiency reduced IFN-β and IFN-γ production. Trim32−/− and WT mice were i.p. injected with 1 × 106 CFUs of Lm. Levels of IFN-β A-C and IFN-γ D-F in serum and in supernatants of homogenized spleens and livers at indicated time points were determined using ELISA. A, D Showed were the combined results of two independent experiments with a total of 10 mice per experimental group and time point B, C, E, F. Data were a representative of three independent experiments. Each symbol represented one mouse. Statistical significance was calculated by means of two-way ANOVA followed by Dunnett’s multiple comparisons test; * P < 0.05, ** P < 0.01

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Gut Pathogens

ISSN: 1757-4749