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Fig. 4 | Gut Pathogens

Fig. 4

From: TRIM32 reduced the recruitment of innate immune cells and the killing capacity of Listeria monocytogenes by inhibiting secretion of chemokines

Fig. 4

Trim32 deficiency enhanced recruitment of macrophages and neutrophils but decreased that of DCs. A Schematic illustration of the gating strategy. (B-D) Relative proportions of neutrophils, macrophages, and DCs in spleen and liver. Trim32−/− and WT mice were i.p. injected with 1 × 106 CFUs of Lm. Mice were sacrificed at 0, 1, 2, and 3 dpi to analyze composition of innate immune cells. Shown were mean ± SEM of 3 mice per experimental group. Data were a representative of three independent experiments. Statistical significance was calculated by means of B–D two-way ANOVA followed by Dunnett’s multiple comparisons test; * P < 0.05, ** P < 0.01

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Gut Pathogens

ISSN: 1757-4749