From: Dysbiosis of gut microbiota during fecal stream diversion in patients with colorectal cancer
Ileostomy (n = 10) | Control (n = 10) | p | |
---|---|---|---|
Sex | |||
Male | 8 (80) | 6 (60) | 0.628 |
Female | 2 (20) | 4 (40) | |
Age (years) | 57.6 ± 7.8 | 63.1 ± 9.5 | 0.174 |
BMI (kg/m2) | 24.1 ± 2.9 | 23.7 ± 3.6 | 0.757 |
ASA score | |||
2 | 8 (80) | 6 (60) | 0.628 |
3 | 2 (20) | 4 (40) | |
Location | |||
Sigmoid and rectosigmoid colon | 0 (0) | 6 (60) | 0.002 |
Upper rectum | 4 (40) | 4 (40) | |
Mid-to-low rectum | 6 (60) | 0 (0) | |
Surgery | |||
AR | 0 (0) | 6 (60) | 0.007 |
LAR | 7 (70) | 4 (40) | |
uLAR (hand-sewn) | 3 (30) | 0 (0) | |
Clinical TNM stage | |||
I | 1 (10) | 3 (30) | 0.513 |
II | 2 (20) | 2 (20) | |
III | 7 (70) | 5 (50) | |
Pathologic TNM stage | |||
0 (complete response) | 1 (10) | 0 (0) | 0.753 |
I | 2 (20) | 3 (30) | |
II | 4 (40) | 4 (40) | |
III | 3 (30) | 3 (30) | |
Neoadjuvant chemoradiotherapy | |||
Performed | 8 (80) | 0 (0) | 0.001 |
Not performed | 2 (20) | 10 (100) | |
Adjuvant chemotherapy | |||
Performed | 10 (100) | 6 (60) | 0.087 |
Not performed | 0 (0) | 4 (40) | |
Time interval between t1 and t2 (months) | 6.0 ± 1.9 | 8.0 ± 2.1 | 0.038 |