Table 3 Cox Proportional Hazards Analysis
From: Gut microbiome dynamics and associations with mortality in critically ill patients
Univariate Models | Variable | Hazard ratio (95% CI) | P value |
|---|---|---|---|
Age | Age | 1 (0.98, 1) | 0.67 |
Sex (male) | Sex (male) | 0.72 (0.37, 1.4) | 0.32 |
Diabetes | Diabetes | 1.1 (0.53, 2.1) | 0.87 |
Malignancy | Malignancy | 1.4 (0.74, 2.7) | 0.29 |
Immunosuppressed | Immunosuppressed | 1.3 (0.65, 2.5) | 0.48 |
Sepsis-3 | Sepsis-3 | 1 (1, 1) | 0.84 |
ARDS | ARDS | 2 (1, 4) | 0.041 |
APACHE II score | APACHE II score | 1.1 (1, 1.1) | 0.01 |
MMI > 0 | MMI > 0 | 2.2 (1.1, 4.3) | 0.017 |
Bivariate Models | |||
(APACHE II score) + ARDS | ARDS | 1.8 (1.0, 3.5) | 0.066 |
(APACHE II score) + ARDS | APACHE II score | 1.1 (1.0, 1.1) | 0.034 |
(APACHE II score) + MMI > 0 | APACHE II score | 1.1 (1.0, 1.1) | 0.0033 |
(APACHE II score) + MMI > 0 | MMI > 0 | 2.5 (1.4, 4.6) | 0.0029 |
ARDS + (MMI > 0) | MMI > 0 | 2.3 (1.2, 4.2) | 0.01 |
ARDS + (MMI > 0) | ARDS | 2.1 (1.1, 4.1) | 0.035 |
Multivariate Models (3 variables) | |||
(APACHE II score) + ARDS + (MMI > 0) | APACHE II score | 1.1 (1.0, 1.1) | 0.0094 |
(APACHE II score) + ARDS + (MMI > 0) | ARDS | 1.9 (1.0, 3.6) | 0.062 |
(APACHE II score) + ARDS + (MMI > 0) | MMI > 0 | 2.5 (1.4, 4.7) | 0.0026 |