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Fig. 3 | Gut Pathogens

Fig. 3

From: Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

Fig. 3

Sequence alignment of the 23S rRNA gene of H. pylori. The base sequence of the 23S rRNA gene fragment of the twelve isolates (UM171, UM626A1, UM650B, and UM678A; S, B, and R) aligned with the base sequence of the reference H. pylori UM032. Position 2143 is highlighted. Multiple sequence alignment was performed using Bioedit version 7.2.5 and CodonCode Aligner version 10.0.3. H. pylori 26695, UM032, and UM233 were susceptible to clarithromycin while H. pylori UM202 and UM370 were resistance to clarithromycin. Common point mutations in A2142G/C and A2143G positions in the 23S rRNA gene of H. pylori 26695 (ATCC 700392), reference strain (UM032), two naturally clarithromycin resistant strains (UM202 and UM370), and a non-induced sensitive strain (UM233) were also included to show the pattern of mutations in comparison to that of the induced isolates

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Gut Pathogens

ISSN: 1757-4749