Table 1 Twenty randomly selected clarithromycin-sensitive H. pylori clinical isolates and one standard strain were inducted by exposure to clarithromycin
No | Isolate | CLR sensitivity/resistance | CLR MIC (µg/mL) | 23S rRNA (A2142G/C) | 23S rRNA (A2143G) | Induction success |
|---|---|---|---|---|---|---|
1 | NCTC 11637 | S | 0.032 | No | No | No |
2 | UM025B | S | 0.032 | No | No | No |
3 | UM067B SW | S | 0.125 | No | No | No |
4 | UM113B | S | 0.125 | No | No | No |
5 | UM113B C5 | S | 0.032 | No | No | No |
6 | UM114 | S | 0.032 | No | No | No |
7 | UM171 | S | 0.064 | No | Yes | Yes |
8 | UM276 R (71) | S | 0.032 | No | No | No |
9 | UM276 S (53) | S | 0.032 | No | No | No |
10 | UM303A C6 | S | 0.032 | No | No | No |
11 | UM408 SW | S | 0.032 | No | No | No |
12 | UM411 SW | S | 0.032 | No | No | No |
13 | UM443A (33) | S | 0.032 | No | No | No |
14 | UM443A SW | S | 0.032 | No | No | No |
15 | UM622A1a | S | 0.032 | No | No | No |
16 | UM626A1 | S | 0.064 | No | Yes | Yes |
17 | UM650B | S | < 0.016 | No | Yes | Yes |
18 | UM663B2 | S | 0.064 | No | No | No |
19 | UM678A | S | 0.064 | No | Yes | Yes |
20 | UM692B2 | S | 0.032 | No | No | No |
21 | UM113A SW | S | 0.032 | No | No | No |
22 | H. pylori 26695 | S | 0.016 | No | No | Not Done |
23 | UM032 | S | 0.016 | No | No | Not Done |
24 | UM202 | R | – | No | No | Not Done |
25 | UM233 | S | – | No | No | Not Done |
26 | UM370 | R | – | No | Yes | Not Done |