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Table 2 MICs of H. pylori isolates before, and after in vitro induction with clarithromycin

From: Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori

No

Isolate

MIC in µg/mL (passage number)

S isolates before induction

B isolates at breakpoint

R isolates after breakpointa

R isolates after resistance inductionb

1

UM171

0.064 (P0)

0.125 (P4)

1 (P5)

> 64 (P10)

2

UM626A1

0.064 (P0)

0.125 (P5)

2 (P6)

> 64 (P11)

3

UM650B

< 0.016 (P0)

0.125 (P7)

1 (P8)

> 64 (P12)

4

UM678A

0.064 (P0)

0.125 (P5)

1 (P6)

> 64 (P10)

  1. aPassage number when isolate developed resistance for the first time
  2. bPassage number when there is no inhibition zone using MIC Test Strip