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Fig. 2 | Gut Pathogens

Fig. 2

From: Strain-resolved metagenomic analysis of the gut as a reservoir for bloodstream infection pathogens among premature infants in Singapore

Fig. 2

Associations between clinical factors and gut microbiome composition. a Bubble plot depicting the amount of variation in gut microbial composition explained by given clinical variables and as measured by PERMANOVA. The size of bubbles represents the amount of variance explained by the variable; asterisks indicate statistical significance (p < 0.05). The first column depicts results from analyses of all samples adjusting for postnatal age; subsequent columns show results from analyses stratified by postnatal age. b Heatmap displaying associations between antibiotic and probiotic exposures and the relative abundances of microbial species within the gut microbiota as estimated by mixed effects linear regression. Only microbial species with a minimum mean relative abundance of 0.01% and a sample prevalence of at least 10% are shown. Boxes are shaded based on the direction and size of the effect as determined from the model beta coefficients; asterisks indicate statistical significance (p < 0.05)

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