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Fig. 3 | Gut Pathogens

Fig. 3

From: Hypoxia exacerbates intestinal injury and inflammatory response mediated by myeloperoxidase during Salmonella Typhimurium infection in mice

Fig. 3

Hypoxia enhances neutrophil and macrophage recruitment in mice during Salmonella infection. Single-cell suspensions of spleens were prepared and stained with anti-CD11b and anti-F4/80 antibodies for macrophages (A) and with anti-CD11b and anti-Ly6G for neutrophils (B). The percentages of CD11b+F4/80+ macrophages (C) and CD11b+ Ly6G+ neutrophils (D) are shown as mean ± SEM (n = 6/group). (E-G) Gene expression of chemoattractant (KC, MCP1, and MIP2) in spleen was analyzed via qPCR (n = 8/group). Significance was analyzed by one-way ANOVA with Tukey’s multiple comparison test (*p < 0.05, **p < 0.01, ***p < 0.001)

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