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Fig. 4 | Gut Pathogens

Fig. 4

From: Hypoxia exacerbates intestinal injury and inflammatory response mediated by myeloperoxidase during Salmonella Typhimurium infection in mice

Fig. 4

Hypoxia augments Salmonella-induced mucosal injury and colitis in mice. (A) Hematoxylin and eosin staining of the colon (×100, ×400). (B) Immunofluorescence microscopy data show the distribution of Salmonella (in green) in colon sections (×200). Levels of TNF-α (C) and IL-1β (D) were determined by quantitative PCR. Cytokine levels of TNF-α (E) and IL-1β (F) were detected by ELISA. Colon levels of KC (G), MCP1 (H), and MIP2 (I) were analyzed by qPCR. Data represent mean ± SEM (n = 8 /group) and one-way ANOVA followed by Tukey’s multiple comparisons test (*p < 0.05; **p < 0.01; ***p < 0.001)

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Gut Pathogens

ISSN: 1757-4749