Fig. 2

Overview of the fecal microbiota composition of the infant stool samples over time. (A) Principal coordinate analysis (PCoA) plot of microbiota variation based on the Bray-Curtis dissimilarity matrix. Blue, samples collected at hospital; red, samples collected in the infant’s home. For each sample, the infant age (in days) was indicated as numbers. Sample collection phase (hospital vs. home) explained 61% of the microbiota variation (PERMANOVA p = 0.006). (B.-D) Microbiota α-diversity of the samples was significantly lower during hospitalization (all Tau-U = 1, p = 0.017) according to observed richness (B), Shannon diversity index (C), and inverse Simpson diversity index (D)