Fig. 7

Bar chart (a) depicting the effect of high-fat diet (3 weeks) and amoxicillin treatment on the relative abundance of the most represented bacterial taxa at the family level for each sample. HFD treatment for 3 weeks in mice showed a significant decrease of Lachnospiraceae and S24-7. Amoxicillin treatment in HFD mice in 3rd week caused a significant increase in Lachnospiraceae and S24-7. The analysis of the color heat map (b) illustrates the mean abuandances of top 13 bacterial community taxa assigned to family. The color intensity in each sample is normalized to represent its relative ratio in the four groups. The color scale of dark red and dark blue represents the higher and lower relative abundances of bacterial communities, respectively. CD: Standard- chow diet for 3 weeks; CD + Amox: Standard- chow diet for 3 weeks and subjected to amoxicillin treatment in 3rd  week; HFD: High-fat diet for 3 weeks; HFD + Amox: High-fat diet for 3 weeks and subjected to amoxicillin treatment in 3rd week