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  1. COVID-19 is an acute respiratory distress syndrome and is often accompanied by gastrointestinal symptoms. The SARS-CoV-2 has been traced not only in nasopharyngeal and mid-nasal swabs but also in stool and rec...

    Authors: Jyoti Chhibber-Goel, Sreehari Gopinathan and Amit Sharma

    Citation: Gut Pathogens 2021 13:14

    Content type: Commentary

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  2. This study aims to characterize, the gut and oral microbiome in Asian subjects with Crohn’s disease (CD) using whole genome shotgun sequencing, thereby allowing for strain-level comparison.

    Authors: Shijia Hu, Eileen Png, Michelle Gowans, David E. H. Ong, Paola Florez de Sessions, Jie Song and Niranjan Nagarajan

    Citation: Gut Pathogens 2021 13:13

    Content type: Research

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  3. The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The do...

    Authors: Jolanta Gruszecka and Rafał Filip

    Citation: Gut Pathogens 2021 13:12

    Content type: Letter to the Editor

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  4. Gastric adenocarcinoma is associated with H. pylori infection and inflammation that can result in the dysbiosis of gastric microbiota. The association of intestinal microbiota with gastric adenocarcinoma subtypes...

    Authors: Virinder Sarhadi, Binu Mathew, Arto Kokkola, Tiina Karla, Milja Tikkanen, Hilpi Rautelin, Leo Lahti, Pauli Puolakkainen and Sakari Knuutila

    Citation: Gut Pathogens 2021 13:11

    Content type: Research

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  5. Clostridioides difficile infection (CDI) is a common hospital-associated diarrhea. Several antibiotics commonly associate with CDI; however, limited data are available on the duration of exposure prior to CDI. Mo...

    Authors: Khadijah M. Alammari and Abrar K. Thabit

    Citation: Gut Pathogens 2021 13:10

    Content type: Research

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  6. Shewanella xiamenensis has been reported in water environment and in patients and can act as the originator of oxacillinase in gram-negative bacteria. In order to assess genome plasticity and its functional prope...

    Authors: Thongpan Leangapichart, Linda Hadjadj, Philippe Gautret and Jean-Marc Rolain

    Citation: Gut Pathogens 2021 13:9

    Content type: Genome Report

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  7. Shiga toxin-producing Escherichia coli (STEC) is a pathotype of E. coli that causes enteric and systemic diseases ranging from diarrhoea to severe hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The...

    Authors: Walid Elmonir, Samar Shalaan, Amin Tahoun, Samy F. Mahmoud, Etab M. Abo Remela, Radwa Eissa, Hanem El-Sharkawy, Mustafa Shukry and Rasha N. Zahran

    Citation: Gut Pathogens 2021 13:8

    Content type: Research

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  8. SARS-CoV-2 has been detected not only in respiratory secretions, but also in stool collections. Here were sought to identify SARS-CoV-2 by enrichment next-generation sequencing (NGS) from fecal samples, and to...

    Authors: Andreas Papoutsis, Thomas Borody, Siba Dolai, Jordan Daniels, Skylar Steinberg, Brad Barrows and Sabine Hazan

    Citation: Gut Pathogens 2021 13:7

    Content type: Research

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  9. Bacillus cereus is ubiquitous in nature, found in environments such as soil, plants, air, and part of the insect and human gut microbiome. The ability to produce endospores and biofilms contribute to their pathog...

    Authors: Balakrishnan N. V. Premkrishnan, Cassie E. Heinle, Akira Uchida, Rikky W. Purbojati, Kavita K. Kushwaha, Alexander Putra, Puramadathil Sasi Santhi, Benjamin W. Y. Khoo, Anthony Wong, Vineeth Kodengil Vettath, Daniela I. Drautz-Moses, Ana Carolina M. Junqueira and Stephan C. Schuster

    Citation: Gut Pathogens 2021 13:6

    Content type: Genome Report

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  10. Intestinal fibrosis is a frequent complication of Crohn’s disease. However, the factors that cause chronicity and promote fibrogenesis are not yet understood.

    Authors: Dina Chokr, Marjorie Cornu, Christel Neut, Clovis Bortolus, Rogatien Charlet, Pierre Desreumaux, Silvia Speca and Boualem Sendid

    Citation: Gut Pathogens 2021 13:5

    Content type: Research

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  11. Campylobacter spp. enteritis is the most frequent bacterial enteritis in both adults and children and is sometimes a source of severe complications. Its diagnosis by culture suffers from a lack of sensitivity and...

    Authors: Justine Franco, Lucie Bénejat, Astrid Ducournau, Francis Mégraud, Philippe Lehours and Emilie Bessède

    Citation: Gut Pathogens 2021 13:4

    Content type: Research

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  12. The emerging intestinal pathogen Campylobacter concisus has been associated with prolonged diarrhoea and classic inflammatory bowel diseases (IBD) and was recently also linked with microscopic colitis (MC). Previ...

    Authors: Marta Emilie Yde Aagaard, Karina Frahm Kirk, Henrik Nielsen and Hans Linde Nielsen

    Citation: Gut Pathogens 2021 13:3

    Content type: Short report

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  13. Inflammatory bowel disease caused by microbial dysbiosis is an important factor contributing to colorectal cancer (CRC) initiation. The ‘driver-passenger’ model in human gut microbial dysbiosis suggests that ‘...

    Authors: Yijia Wang, Xuehua Wan, Xiaojing Wu, Chunze Zhang, Jun Liu and Shaobin Hou

    Citation: Gut Pathogens 2021 13:2

    Content type: Research

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  14. Colorectal adenomatous polyps (CAPs) are considered precancerous lesions of colorectal cancer (CRC). The gut microbiota participates in the process of digestion and, in the process, produces metabolites, mainl...

    Authors: Ciyan Chen, Min Niu, Junxi Pan, Na Du, Shumin Liu, Huanqin Li, Qiuyue He, Jian Mao, Yong Duan and Yan Du

    Citation: Gut Pathogens 2021 13:1

    Content type: Research

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  15. Helicobacter pullorum commonly colonized in the gastrointestinal tract of poultry and caused gastroenteritis. This bacterium could be transmitted to humans through contaminated food and caused colitis and hepatit...

    Authors: Guilan Zhou, Hao Liang, Yixin Gu, Changyan Ju, Lihua He, Pengbo Guo, Zhujun Shao, Jianzhong Zhang and Maojun Zhang

    Citation: Gut Pathogens 2020 12:56

    Content type: Research

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  16. The emergence and transmission of the mobile colistin resistance gene (mcr-1) threatened the extensive use of polymyxin antimicrobials. Accumulated evidence showed that the banning of colistin additive in livesto...

    Authors: Cong Shen, Lan-Lan Zhong, Furong Ma, Mohamed Abd El-Gawad El-Sayed Ahmed, Yohei Doi, Guili Zhang, Yang Liu, Songyin Huang, Hong-Yu Li, Liyan Zhang, Kang Liao, Yong Xia, Min Dai, Bin Yan and Guo-Bao Tian

    Citation: Gut Pathogens 2020 12:55

    Content type: Short report

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  17. The global emergence of plasmid-mediated colistin resistance (Col-R) conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment option for multidrug-resistant bacterial infections in h...

    Authors: Humera Javed, Sidrah Saleem, Aizza Zafar, Aamir Ghafoor, Ahmad Bin Shahzad, Hasan Ejaz, Kashaf Junaid and Shah Jahan

    Citation: Gut Pathogens 2020 12:54

    Content type: Research

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  18. Cathelicidins are a class of antimicrobial peptide, and the murine cathelicidin-related antimicrobial peptide (mCRAMP) has been demonstrated in vitro to impair Salmonella enterica serovar Typhimurium proliferatio...

    Authors: Danisa M. Bescucci, Sandra T. Clarke, Catherine L. J. Brown, Valerie F. Boras, Tony Montina, Richard R. E. Uwiera and G. Douglas Inglis

    Citation: Gut Pathogens 2020 12:53

    Content type: Research

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  19. Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP. Yet, the impact of long-term antibiotic prophylaxis on the m...

    Authors: Marcus M. Mücke, Sabrina Rüschenbaum, Amelie Mayer, Victoria T. Mücke, Katharina M. Schwarzkopf, Stefan Zeuzem, Jan Kehrmann, René Scholtysik and Christian M. Lange

    Citation: Gut Pathogens 2020 12:51

    Content type: Research

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  20. Increasing evidence demonstrate that the gut microbiota is involved in the pathogenesis of liver diseases, and faecal microbiota transplantation is considered to be a promising new treatment option. However, t...

    Authors: Xiu-An Yang, Fengchun Lv, Ran Wang, Yange Chang, Yiming Zhao, Xinyu Cui, Haochen Li, Sixi Yang, Suting Li, Xuemin Zhao, Zhishuo Mo and Fang Yang

    Citation: Gut Pathogens 2020 12:50

    Content type: Research

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  21. The steady increase in the proportion of Non-typhoidal Salmonella (NTS) infections in humans represents a major health problem worldwide. The current study investigated the serovar distribution and antimicrobial ...

    Authors: Jobin John Jacob, Dhanalakshmi Solaimalai, Dhiviya Prabaa Muthuirulandi Sethuvel, Tanya Rachel, Praveena Jeslin, Shalini Anandan and Balaji Veeraraghavan

    Citation: Gut Pathogens 2020 12:49

    Content type: Research

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  22. MiR-146a, an effector mediator, targets Notch-1 and regulates the innate and adaptive immune systems response. Recently, we reported that Notch-1 signaling plays a key role in macrophage polarization and respo...

    Authors: Esra’a Keewan and Saleh A. Naser

    Citation: Gut Pathogens 2020 12:48

    Content type: Research

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  23. Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylatio...

    Authors: Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens and John M. Carethers

    Citation: Gut Pathogens 2020 12:46

    Content type: Letter to the Editor

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  24. Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs)...

    Authors: Josué Orozco-Aguilar, Alejandro Alfaro-Alarcón, Luis Acuña-Amador, Esteban Chaves-Olarte, César Rodríguez and Carlos Quesada-Gómez

    Citation: Gut Pathogens 2020 12:45

    Content type: Research

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  25. Plasmid-mediated resistance to the last-resort drugs: carbapenems and colistin is an emerging public health threat. The studies on the prevalence and co-expression of resistant genes among livestock and human ...

    Authors: Bijaya Muktan, Upendra Thapa Shrestha, Binod Dhungel, Bagish Chandra Mishra, Nabaraj Shrestha, Nabaraj Adhikari, Megha Raj Banjara, Bipin Adhikari, Komal Raj Rijal and Prakash Ghimire

    Citation: Gut Pathogens 2020 12:44

    Content type: Research

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  26. Community-acquired urinary tract infection (CA-UTI) could be caused by endogenous or exogenous routes. To show this relationship, we investigated molecular fingerprints and genotypes of paired Enterococcus faecal...

    Authors: Zohreh Ghalavand, Masoud Alebouyeh, Kiandokht Ghanati, Leila Azimi and Marjan Rashidan

    Citation: Gut Pathogens 2020 12:42

    Content type: Research

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  27. Colistin is still a widely used antibiotic in veterinary medicine although it is a last-line treatment option for hospitalized patients with infections caused by multidrug-resistant Gram-negative bacteria. Col...

    Authors: Bernd Neumann, Wiebke Rackwitz, Klaus-Peter Hunfeld, Stephan Fuchs, Guido Werner and Yvonne Pfeifer

    Citation: Gut Pathogens 2020 12:40

    Content type: Genome Report

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  28. After the failure of clarithromycin- and bismuth-based quadruple therapy (CBQT), levofloxacin- and bismuth-based quadruple therapy (LBQT) is recommended for Helicobacter pylori eradication. We compared the effica...

    Authors: Siya Kong, Keting Huang, Jun Wang, Xiaoyong Wang, Ningmin Yang, Yu Dong, Ya Zhuang, Yini Dang, Guoxin Zhang and Feng Ye

    Citation: Gut Pathogens 2020 12:39

    Content type: Research

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  29. Intestinal bacterial dysbiosis and increased gut permeability are associated with higher risk of developing type 1 diabetes (T1D) or celiac disease (CD). There is a lack of information on parasitism involved i...

    Authors: Ana M. Calderón de la Barca, Reyna S. Castillo-Fimbres, María Esther Mejía-León, Luis Quihui-Cota, Adrián Ochoa-Leyva and Sandra V. Aguayo-Patrón

    Citation: Gut Pathogens 2020 12:37

    Content type: Research

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  30. Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations. To effectively treat patient...

    Authors: Yangxia Li, Tangshan Lv, Chaochao He, Hongyan Wang, David S. Cram, Linfu Zhou, Jun Zhang and Weiqin Jiang

    Citation: Gut Pathogens 2020 12:35

    Content type: Research

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  31. Hypervirulent Klebsiella pneumoniae (HVKp) infections have distinct clinical manifestations from classical K. pneumoniae infections. The hallmark of HVKp infections are liver abscess formation and metastatic infe...

    Authors: Atsushi Togawa, Michinobu Yoshimura, Chiemi Tokushige, Akira Matsunaga, Tohru Takata and Yasushi Takamatsu

    Citation: Gut Pathogens 2020 12:34

    Content type: Research

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  32. Metagenomic analysis of the gut microbiome and resistome is instrumental for understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance transmission (AMR). Metagenomic sequencing of 20 d...

    Authors: Rituparna De, Asish Kumar Mukhopadhyay and Shanta Dutta

    Citation: Gut Pathogens 2020 12:32

    Content type: Research

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  33. Helicobacter pylori colonises the stomach of approximately 50% of the global population. Cytotoxin-associated gene A protein (CagA) is one of the important virulent factors responsible for the increased inflammat...

    Authors: Shaohan Xu, Xiaoqian Wu, Xiaoyan Zhang, Chu Chen, Hao Chen and Feifei She

    Citation: Gut Pathogens 2020 12:31

    Content type: Research

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  34. Acute gastroenteritis (AGE) is diagnosed with a presentation of > 1 episode of vomiting and > 3 episodes of diarrhea in a 24-h period. Treatment is supportive, however, in severe cases antibacterial treatment ...

    Authors: Omar Fraij, Neva Castro, Luis A. de Leon Castro and Lawrence J. Brandt

    Citation: Gut Pathogens 2020 12:30

    Content type: Research

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  35. Personal Protective Equipment (PPE) is required to safely work with biological agents of bacterial (i.e. Mycobacterium tuberculosis) or viral origin (Ebola and SARS). COVID-19 pandemic especially has created unfo...

    Authors: Vikram Saini, Kriti Sikri, Sakshi Dhingra Batra, Priya Kalra and Kamini Gautam

    Citation: Gut Pathogens 2020 12:29

    Content type: Short report

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  36. Enterotoxigenic Bacteroides fragilis (ETBF) associated with the initiation and progression of colorectal cancer (CRC) has been alarmingly reported all over the world. In this study, simultaneous investigation of ...

    Authors: Seyedesomaye Jasemi, Mohammad Emaneini, Mohammad Sadegh Fazeli, Zahra Ahmadinejad, Bizhan Nomanpour, Fatemah Sadeghpour Heravi, Leonardo A. Sechi and Mohammad Mehdi Feizabadi

    Citation: Gut Pathogens 2020 12:28

    Content type: Research

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  37. Intestinal parasitic diseases occur worldwide, and their diagnosis poses considerable challenges. Cryptosporidium spp., Entamoeba histolytica, Giardia intestinalis, (and, arguably, Dientamoeba fragilis and Blasto...

    Authors: Aline Lamien-Meda, Renate Schneider, Julia Walochnik, Herbert Auer, Ursula Wiedermann and David Leitsch

    Citation: Gut Pathogens 2020 12:27

    Content type: Research

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  38. The global epidemic of nosocomial diarrhea caused by Clostridioides (Clostridium) difficile started in 2000, with high mortality rates and emergence of a new hypervirulent strain NAP1/BI/027. The aim of this stud...

    Authors: Miloš Korać, Maja Rupnik, Nataša Nikolić, Milica Jovanović, Tanja Tošić, Jovan Malinić, Nikola Mitrović, Marko Marković, Ankica Vujović, Sanja Peruničić, Ksenija Bojović, Vladimir Djordjević, Aleksandra Barać and Ivana Milošević

    Citation: Gut Pathogens 2020 12:26

    Content type: Research

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  39. Helicobacter pylori typically colonizes the human stomach, but it can occasionally be detected in the oral cavity of infected persons. Clinical outcome as a result of gastric colonization depends on presence of t...

    Authors: Nicole Tegtmeyer, Tabita Denisia Ghete, Verena Schmitt, Torsten Remmerbach, Maria Celeste C. Cortes, Edgardo M. Bondoc, Hans-Ludwig Graf, Bernhard B. Singer, Christian Hirsch and Steffen Backert

    Citation: Gut Pathogens 2020 12:25

    Content type: Research

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  40. This study utilized a chicken model of chronic physiological stress mediated by corticosterone (CORT) administration to ascertain how various host metrics are altered upon challenge with Clostridium perfringens. ...

    Authors: Sarah J. M. Zaytsoff, Sarah M. Lyons, Alexander M. Garner, Richard R. E. Uwiera, Wesley F. Zandberg, D. Wade Abbott and G. Douglas Inglis

    Citation: Gut Pathogens 2020 12:24

    Content type: Research

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  41. Emerging evidence closely links Enterovirus 71 (EV71) infection with the generation of reactive oxygen species (ROS). Excess ROS results in apoptosis and exacerbates inflammatory reactions. The Keap1–Nrf2 axis...

    Authors: Zhenzi Bai, Xiaonan Zhao, Chenghua Li, Chuanlun Sheng and Hongyan Li

    Citation: Gut Pathogens 2020 12:22

    Content type: Research

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  42. With the rise of bacterial resistance to conventional antibiotics, re-purposing of Food and Drug Administration (FDA) approved drugs currently used to treat non-bacteria related diseases as new leads for antib...

    Authors: Mohammad M. Rahman, Alexandra Tikhomirova, Joyanta K. Modak, Melanie L. Hutton, Claudiu T. Supuran and Anna Roujeinikova

    Citation: Gut Pathogens 2020 12:20

    Content type: Short report

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