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  1. The role of the gut microbiome in human health and disease with a particular emphasis on therapeutic use of probiotics under specific medical conditions was mainly highlighted in 1st Annual conference of Probi...

    Authors: Sunita Grover, Hogarehalli Mallapa Rashmi, Anil Kumar Srivastava and Virender Kumar Batish

    Citation: Gut Pathogens 2012 4:15

    Content type: Meeting report

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  2. Campylobacter jejuni and coli are collectively regarded as the most prevalent cause of bacterial foodborne illness worldwide. An emerging species, Campylobacter ureolyticus has recently been detected in patients ...

    Authors: Monika Koziel, Brigid Lucey, Susan Bullman, Gerard D Corcoran and Roy D Sleator

    Citation: Gut Pathogens 2012 4:14

    Content type: Short report

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  3. Recently, we found that the probiotic strain Bacillus coagulans GBI-30, 6086 (GanedenBC30) improved indices of Clostridium difficile (C. difficile)-induced colitis in mice (Fitzpatrick et al., Gut Pathogens, 2011...

    Authors: Leo R Fitzpatrick, Jeffrey S Small, Wallace H Greene, Kelly D Karpa, Sean Farmer and David Keller

    Citation: Gut Pathogens 2012 4:13

    Content type: Research

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  4. Following Helicobacter pylori eradication in idiopathic parkinsonism (IP), hypokinesia improved but flexor-rigidity increased. Small intestinal bacterial-overgrowth (SIBO) is a candidate driver of the rigidity: h...

    Authors: R John Dobbs, André Charlett, Sylvia M Dobbs, Clive Weller, Mohammad A A Ibrahim, Owens Iguodala, Cori Smee, J Malcolm Plant, Andrew J Lawson, David Taylor and Ingvar Bjarnason

    Citation: Gut Pathogens 2012 4:12

    Content type: Research

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  5. The foodborne pathogen Bacillus cereus can cause diarrhoeal food poisoning by production of enterotoxins in the small intestine. The prerequisite for diarrhoeal disease is thus survival during gastrointestinal pa...

    Authors: Siele Ceuppens, Mieke Uyttendaele, Stefanie Hamelink, Nico Boon and Tom Van de Wiele

    Citation: Gut Pathogens 2012 4:11

    Content type: Research

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  6. Mycobacterium avium subsp. paratuberculosis (MAP) is a zoonotic pathogen, a very slow growing bacterium which is difficult to isolate and passage in conventional laboratory culture. Although its association with ...

    Authors: Pittu Sandhya Rani, Nikhil Kumar Tulsian, Leonardo A Sechi and Niyaz Ahmed

    Citation: Gut Pathogens 2012 4:10

    Content type: Short report

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  7. Helicobacter pylori are successful colonizers of the human gastric mucosa. Colonization increases the risk of peptic ulcer disease and adenocarcinoma. However, potential benefits of H. pylori colonization include...

    Authors: Sabine Kienesberger, Guillermo I Perez-Perez, Juan L Rivera-Correa, Rafael Tosado-Acevedo, Huilin Li, Andre Dubois, Janis A Gonzalez-Martinez, Maria Gloria Dominguez-Bello and Martin J Blaser

    Citation: Gut Pathogens 2012 4:9

    Content type: Research

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  8. “Quorum sensing” (QS) is the phenomenon which allows single bacterial cells to measure the concentration of bacterial signal molecules. Two principle different QS systems are known, the Autoinducer 1 system (A...

    Authors: Christoph A Jacobi, Stefanie Grundler, Chih-Jen Hsieh, Julia Stefanie Frick, Patrick Adam, Georg Lamprecht, Ingo B Autenrieth, Michael Gregor and Peter Malfertheiner

    Citation: Gut Pathogens 2012 4:8

    Content type: Research

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  9. Klebsiella pneumoniae carbapenemases (KPCs) producing bacteria have emerged as a cause of multidrug-resistant nosocomial infections worldwide. KPCs are plasmid-encoded enzymes capable of hydrolysing a broad spect...

    Authors: Sara N Richter, Ilaria Frasson, Elisa Franchin, Cristina Bergo, Enrico Lavezzo, Luisa Barzon, Antonietta Cavallaro and Giorgio Palù

    Citation: Gut Pathogens 2012 4:7

    Content type: Research

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  10. Inflammatory Bowel Disease (IBD), which includes both Crohn’s disease (CD) and ulcerative colitis (UC), is caused by a complex interplay involving genetic predisposition, environmental factors and an infectiou...

    Authors: Natalia Elguezabal, Susana Chamorro, Elena Molina, Joseba M Garrido, Ander Izeta, Luis Rodrigo and Ramón A Juste

    Citation: Gut Pathogens 2012 4:6

    Content type: Research

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  11. Many Gram-positive and Gram-negative bacteria produce large quantities of indole as an intercellular signal in microbial communities. Indole demonstrated to affect gene expression in Escherichia coli as an intra-...

    Authors: Eiji Nikaido, Etienne Giraud, Sylvie Baucheron, Suguru Yamasaki, Agnès Wiedemann, Kousuke Okamoto, Tatsuya Takagi, Akihito Yamaguchi, Axel Cloeckaert and Kunihiko Nishino

    Citation: Gut Pathogens 2012 4:5

    Content type: Research

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  12. Infection with Helicobacter pylori strains that express CagA is associated with gastritis, peptic ulcer disease, and gastric adenocarcinoma. The biological function of CagA depends on tyrosine phosphorylation by ...

    Authors: Santanu Chattopadhyay, Rajashree Patra, Raghunath Chatterjee, Ronita De, Jawed Alam, T Ramamurthy, Abhijit Chowdhury, G Balakrish Nair, Douglas E Berg and Asish K Mukhopadhyay

    Citation: Gut Pathogens 2012 4:4

    Content type: Research

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  13. Campylobacter jejuni is one of the most important bacterial pathogens causing food-borne illness worldwide. Crossing the intestinal epithelial barrier and host cell entry by C. jejuni is considered the primary re...

    Authors: Manja Boehm, Benjamin Hoy, Manfred Rohde, Nicole Tegtmeyer, Kristoffer T Bæk, Omar A Oyarzabal, Lone Brøndsted, Silja Wessler and Steffen Backert

    Citation: Gut Pathogens 2012 4:3

    Content type: Research

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  14. Vibrio cholerae is the causative organism of waterborne disease, cholera. V. cholerae has caused many epidemics and pandemics of cholera for many years. In this study, V. cholerae recovered from edible ice were i...

    Authors: Diana E Waturangi, Ignasius Joanito, Yogiara Yogi and Sabu Thomas

    Citation: Gut Pathogens 2012 4:2

    Content type: Research

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  15. Our understanding of the role of the microbiota in our gut and other sites in our body is rapidly emerging and could lead to many new and innovative approaches for health care. The promise of the potential rol...

    Authors: Neerja Hajela, G Balakrish Nair, Philip Abraham and Nirmal K Ganguly

    Citation: Gut Pathogens 2012 4:1

    Content type: Meeting report

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  16. We report an ongoing outbreak of ulcerative colitis and Crohn's disease in Forest, Virginia involving 15 unrelated children and teenagers who resided in close proximity to dairy farms. Some of our cases demons...

    Authors: Ellen S Pierce, Stephen M Borowitz and Saleh A Naser

    Citation: Gut Pathogens 2011 3:20

    Content type: Case report

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  17. We investigated the interaction of Mycobacterium avium subspecies paratuberculosis, M. bovis and M. tuberculosis and different glial cells (enteric glial and microglial cells) in order to evaluate the infecting a...

    Authors: Sara Cannas, Paola Molicotti, Alessandra Bua, Donatella Usai, Leonardo A Sechi, Antonio M Scanu, Elisabetta Blasi and Stefania Zanetti

    Citation: Gut Pathogens 2011 3:19

    Content type: Research

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  18. Ruminants, in particular bovines, are the primary reservoir of Shiga toxin-producing E. coli (STEC), but whole genome analyses of the current German ESBL-producing O104:H4 outbreak strain of sequence type (ST) 67...

    Authors: Lothar H Wieler, Torsten Semmler, Inga Eichhorn, Esther M Antao, Bianca Kinnemann, Lutz Geue, Helge Karch, Sebastian Guenther and Astrid Bethe

    Citation: Gut Pathogens 2011 3:17

    Content type: Research

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  19. Probiotics have beneficial effects in rodent models of Clostridium difficile (C. diffiicle)-induced colitis. The spore forming probiotic strain Bacillus Coagulans GBI-30, 6086 (BC30) has demonstrated anti-inflamm...

    Authors: Leo R Fitzpatrick, Jeffrey S Small, Wallace H Greene, Kelly D Karpa and David Keller

    Citation: Gut Pathogens 2011 3:16

    Content type: Research

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  20. Several studies have shown that significant genotypic heterogeneity exists among Campylobacter concisus strains. Recently, the genome of C. concisus UNSWCD, isolated from a patient with Crohn's disease, was seque...

    Authors: Nadeem O Kaakoush, Nandan P Deshpande, Marc R Wilkins, Mark J Raftery, Karolina Janitz and Hazel Mitchell

    Citation: Gut Pathogens 2011 3:15

    Content type: Research

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  21. The development of efficacious alternatives to antimicrobial growth promoters (AGP) in livestock production is an urgent issue, but is hampered by a lack of knowledge regarding the mode of action of AGP. The b...

    Authors: Estela Costa, Richard RE Uwiera, John P Kastelic, L Brent Selinger and G Douglas Inglis

    Citation: Gut Pathogens 2011 3:14

    Content type: Research

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  22. The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively...

    Authors: Ilaria Frasson, Antonietta Cavallaro, Cristina Bergo, Sara N Richter and Giorgio Palù

    Citation: Gut Pathogens 2011 3:12

    Content type: Short report

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  23. Campylobacter jejuni, a gram-negative bacterium, is a frequent cause of gastrointestinal food-borne illness in humans throughout the world. There are several reports that the virulence of C. jejuni might be modul...

    Authors: Piyarat Pootong, Oralak Serichantalergs, Ladaporn Bodhidatta, Frédéric Poly, Patricia Guerry and Carl J Mason

    Citation: Gut Pathogens 2011 3:11

    Content type: Research

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  24. Contamination from fecal bacteria in recreational waters is a major health concern since bacteria capable of causing human disease can be found in animal feces. The Dog Beach area of Ocean Beach in San Diego, ...

    Authors: Veronica Casas, Gerico Sobrepeña, Beltran Rodriguez-Mueller, Justine AhTye and Stanley R Maloy

    Citation: Gut Pathogens 2011 3:10

    Content type: Research

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  25. Apart from localized gastrointestinal infections, Escherichia coli and Salmonella species are major causes of systemic disease in both humans and animals. Salmonella spp. cause invasive infections such as enteric...

    Authors: Mary A Bisi-Johnson, Chikwelu L Obi, Sandeep D Vasaikar, Kamaldeen A Baba and Toshio Hattori

    Citation: Gut Pathogens 2011 3:9

    Content type: Research

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  26. Recent research on obesity has demonstrated that the intestinal microflora can have an important influence on host energy balance. The aim of the study was to investigate the relationship between the intestina...

    Authors: Carl Vael, Stijn L Verhulst, Vera Nelen, Herman Goossens and Kristine N Desager

    Citation: Gut Pathogens 2011 3:8

    Content type: Research

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  27. Malnutrition, a major health problem, affects a significant proportion of preschool children in developing countries. The devastating consequences of malnutrition include diarrhoea, malabsorption, increased in...

    Authors: Sourav Sen Gupta, Monzoorul Haque Mohammed, Tarini Shankar Ghosh, Suman Kanungo, Gopinath Balakrish Nair and Sharmila S Mande

    Citation: Gut Pathogens 2011 3:7

    Content type: Research

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  28. Helicobacter pylori is an important agent of gastroduodenal disease in Africa and throughout the world. We sought to determine an optimum method for genotyping H. pylori strains from children and adults in The Ga...

    Authors: Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A Adegbola and Julian E Thomas

    Citation: Gut Pathogens 2011 3:5

    Content type: Research

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  29. Enteroaggregative Escherichia coli (EAEC) are important diarrhoeal pathogens that are defined by a HEp-2 adherence assay performed in specialist laboratories. Multilocus sequence typing (MLST) has revealed that a...

    Authors: Iruka N Okeke, Louissa R Macfarlane-Smith, Jonathan N Fletcher and Anna M Snelling

    Citation: Gut Pathogens 2011 3:4

    Content type: Research

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  30. Helicobacter pylori (H. pylori) is a micro-aerophilic, spiral-shaped, motile bacterium that is the principal cause of gastric and duodenal ulcers in humans and is a major risk factor for the development of gastri...

    Authors: Glenn N Borlace, Hilary F Jones, Stacey J Keep, Ross N Butler and Doug A Brooks

    Citation: Gut Pathogens 2011 3:3

    Content type: Research

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  31. The intestinal microbiota plays an important role in immune development and homeostasis. A disturbed microbiota during early infancy is associated with an increased risk of developing inflammatory and allergic...

    Authors: Paul V Licciardi, Sook-San Wong, Mimi LK Tang and Tom C Karagiannis

    Citation: Gut Pathogens 2010 2:24

    Content type: Hypothesis

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  32. Egg-associated transmission to humans seems to be characteristic of the Salmonella serotype Enteritidis, explaining why this particular serotype has caused a worldwide pandemic since the mid '80s. Salmonella Ente...

    Authors: Filip Van Immerseel

    Citation: Gut Pathogens 2010 2:23

    Content type: Hypothesis

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  33. Campylobacter jejuni is a significant cause of bacterial enteritis worldwide. Very little is known about the pathogenicity mechanisms and virulence factors of this important enteropathogen. C. jejuni isolates fro...

    Authors: Benjamin Feodoroff, Patrik Ellström, Heidi Hyytiäinen, Seppo Sarna, Marja-Liisa Hänninen and Hilpi Rautelin

    Citation: Gut Pathogens 2010 2:22

    Content type: Research

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  34. Recent studies have suggested a role for an altered intestinal microbiota in the pathophysiology of irritable bowel syndrome (IBS). However, no consensus has been reached regarding the association between spec...

    Authors: Ian M Carroll, Young-Hyo Chang, Jiwon Park, R Balfour Sartor and Yehuda Ringel

    Citation: Gut Pathogens 2010 2:19

    Content type: Research

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  35. Shigella is a frequent cause of bacterial dysentery in the developing world. Treatment with effective antibiotics is recommended for shigellosis, but options become limited due to globally emerging resistance....

    Authors: Ruslan S Madiyarov, Amir M Bektemirov, Gulnara A Ibadova, Gulnara K Abdukhalilova, Aybek V Khodiev, Ladaporn Bodhidatta, Orntipa Sethabutr and Carl J Mason

    Citation: Gut Pathogens 2010 2:18

    Content type: Research

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  36. A total of 225 isolates of Salmonella enterica serovar Typhimurium from food-producing animals collected between 2003 and 2007 were examined for the prevalence of plasmid-mediated quinolone resistance (PMQR) dete...

    Authors: Tetsuo Asai, Chizuru Sato, Kaori Masani, Masaru Usui, Manao Ozawa, Tomoe Ogino, Hiroshi Aoki, Takuo Sawada, Hidemasa Izumiya and Haruo Watanabe

    Citation: Gut Pathogens 2010 2:17

    Content type: Short report

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  37. Pseudomonas fluorescens has long been considered as a psychrotrophic microorganism. Recently, we have shown that clinical strains of P. fluorescens (biovar 1) are able to adapt at a growth temperature of 37°C or ...

    Authors: Amar Madi, Pascal Svinareff, Nicole Orange, Marc GJ Feuilloley and Nathalie Connil

    Citation: Gut Pathogens 2010 2:16

    Content type: Research

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  38. Campylobacter jejuni is a major cause of gastroenteritis worldwide. In Thailand, several strains of C. jejuni have been isolated and identified as major diarrheal pathogens among adult travelers. To study the epi...

    Authors: Oralak Serichantalergs, Piyarat Pootong, Anders Dalsgaard, Ladaporn Bodhidatta, Patricia Guerry, David R Tribble, Sinn Anuras and Carl J Mason

    Citation: Gut Pathogens 2010 2:15

    Content type: Research

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  39. Recent epidemiological analyses have implicated acute Campylobacter enteritis as a factor that may incite or exacerbate inflammatory bowel disease (IBD) in susceptible individuals. We have demonstrated previously...

    Authors: Lisa D Kalischuk, Frances Leggett and G Douglas Inglis

    Citation: Gut Pathogens 2010 2:14

    Content type: Research

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  40. In 2005, the first disease-specific Helicobacter pylori virulence factor that induced duodenal ulcer and had a suppressive action on gastric cancer has been identified, and was named duodenal ulcer promoting gene...

    Authors: Seiji Shiota, Osamu Matsunari, Masahide Watada, Katsuhiro Hanada and Yoshio Yamaoka

    Citation: Gut Pathogens 2010 2:13

    Content type: Review

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  41. Entamoeba histolytica infection is found almost all over the world and is highly endemic and a major cause of parasitic diarrhoea particularly in the developing countries.

    Authors: Avik K Mukherjee, Kaushik Das, Mihir K Bhattacharya, Tomoyoshi Nozaki and Sandipan Ganguly

    Citation: Gut Pathogens 2010 2:12

    Content type: Letter to the Editor

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  42. Mycobacterium avium subsp. paratuberculosis (MAP) causes a chronic gastroenteritis affecting many species. Johne's disease is one of the most widespread and economically important disease of ruminants. Since 1992...

    Authors: Pierre E Douarre, William Cashman, Jim Buckley, Aidan Coffey and Jim M O'Mahony

    Citation: Gut Pathogens 2010 2:11

    Content type: Research

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