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  1. Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host–pathogen interactions is still li...

    Authors: Anna-Maria Schmidt, Ulrike Escher, Soraya Mousavi, Nicole Tegtmeyer, Manja Boehm, Steffen Backert, Stefan Bereswill and Markus M. Heimesaat
    Citation: Gut Pathogens 2019 11:24
  2. Recently, intestinal microbiome has been involved in hepatic diseases due to the immunologic and metabolic communication between liver and intestine. Initiation of hepatocellular carcinoma (HCC) frequently att...

    Authors: Xiao Han, Tianren Huang and Junqing Han
    Citation: Gut Pathogens 2019 11:23
  3. Due to increased prevalence of H. pylori antimicrobial resistance worldwide and more importantly the resistance patterns vary between different geographical regions, it is important to survey local H. pylori anti...

    Authors: Vignesh Shetty, Binit Lamichhane, Chin Yen Tay, Ganesh C. Pai, Ramachandra Lingadakai, Girisha Balaraju, Shiran Shetty, Mamatha Ballal and Eng Guan Chua
    Citation: Gut Pathogens 2019 11:21
  4. Gut microbiota affects lipid metabolism interactively with diet. Equol, a metabolite of isoflavones produced by gut bacteria, may contribute substantially in beneficial lipid-lowering effects. This study aimed...

    Authors: Wei Zheng, Yue Ma, Ai Zhao, Tingchao He, Na Lyu, Ziqi Pan, Geqi Mao, Yan Liu, Jing Li, Peiyu Wang, Jun Wang, Baoli Zhu and Yumei Zhang
    Citation: Gut Pathogens 2019 11:20
  5. Campylobacter is the most common cause of traveler’s diarrhea (TD) and human bacterial gastroenteritis. A heteroresistant Campylobacter jejuni (C. jejuni) isolate, identified by microbiological methods and charac...

    Authors: Woradee Lurchachaiwong, Supaporn Ruksasiri, Patcharawalai Wassanarungroj, Oralak Serichantalergs, Ladaporn Bodhidatta, John Crawford, Sanjaya Kumar Shrestha and Prativa Pandey
    Citation: Gut Pathogens 2019 11:19
  6. Chemotherapy induced diarrhea (CID) is a common side effect in patients receiving chemotherapy for cancer. The aim of our study was to explore the association between gut microorganisms and CID from the CapeOX...

    Authors: Zuo Fei, Yin Lijuan, Yang Xi, Wu Wei, Zhong Jing, Da Miao and Han Shuwen
    Citation: Gut Pathogens 2019 11:18
  7. Surveillance of Clostridium difficile infection (CDI) in patients with underlying diseases is important because use of prophylactic antibiotics makes them prone to CDI. Epidemiology of CDI in this high-risk popul...

    Authors: Chetana Vaishnavi, Pramod K. Gupta, Megha Sharma and Rakesh Kochhar
    Citation: Gut Pathogens 2019 11:17
  8. The serious human pathogen, E. coli serotype O157:H7, continues to gain antibiotic resistance, posing a public health threat. While this serotype’s genome has been sequenced, the role of 25% of its genes remains ...

    Authors: Salma H. Hussein, Reham Samir, Ramy K. Aziz and Mohamed A. Toama
    Citation: Gut Pathogens 2019 11:15
  9. Metagenomic methods have been widely applied to study the relationship between gut microbiota and human health. To test whether metagenomic amplicon sequencing could be an effective method to diagnose and trac...

    Authors: Haiyan Liu, Mingzhang Guo, Yuanchunzi Jiang, Yanhua Cao, Qingzeng Qian, Xiaoyun He, Kunlun Huang, Jianwei Zhang and Wentao Xu
    Citation: Gut Pathogens 2019 11:12
  10. Cryptosporidium is an important gut microbe whose contributions towards infant and immunocompromise patient mortality rates are steadily increasing. Over the last decade, we have seen the development of various t...

    Authors: Christopher N. Miller, Charalampos G. Panagos, William R. T. Mosedale, Martin Kváč, Mark J. Howard and Anastasios D. Tsaousis
    Citation: Gut Pathogens 2019 11:13
  11. In Asia, serotype K1/K2 Klebsiella pneumoniae are the major capsular serotypes that cause liver abscess or bacteremia in patients. The purpose of this study was to compare novel immunochromatographic strips (ICSs...

    Authors: Ching-Hsun Wang, Po-Liang Lu, Esther Yip-Mei Liu, Yih-Yuan Chen, Fu-Mei Lin, Yi-Tsung Lin, Feng-Yee Chang and Jung-Chung Lin
    Citation: Gut Pathogens 2019 11:11
  12. Extraintestinal pathogenic E. coli (ExPEC) are facultative pathogens that are part of the normal human intestinal flora. The ExPEC group includes uropathogenic E. coli (UPEC), neonatal meningitis E. coli (NMEC), ...

    Authors: Jolanta Sarowska, Bozena Futoma-Koloch, Agnieszka Jama-Kmiecik, Magdalena Frej-Madrzak, Marta Ksiazczyk, Gabriela Bugla-Ploskonska and Irena Choroszy-Krol
    Citation: Gut Pathogens 2019 11:10
  13. Enterotoxigenic Escherichia coli (ETEC) is a common cause of bacterial infection that leads to diarrhea. Although some studies have proposed a potential association between the toxic profile and genetic backgroun...

    Authors: Si-yun Chung, Taesoo Kwon, Young-Seok Bak, Joung Je Park, Cheorl-Ho Kim, Seung-Hak Cho and Won Kim
    Citation: Gut Pathogens 2019 11:9
  14. The relationship between disturbances of the gut microbiota and 1,25(OH)2D3 deficiency has been established both in humans and animal models with a vitamin D poor diet or a lack of sun exposure. Our prior study h...

    Authors: Wenjing Zhu, Jiayao Yan, Chunchun Zhi, Qianwen Zhou and Xiaoqin Yuan
    Citation: Gut Pathogens 2019 11:8
  15. Helicobacter pylori is a Gram-negative bacterium which mainly causes peptic ulcer disease in human, but is also the predominant cause of stomach cancer. It has been coevolving with human since 120,000 years and, ...

    Authors: Binit Lamichhane, Eng-Guan Chua, Michael J. Wise, Connor Laming, Barry J. Marshall and Chin-Yen Tay
    Citation: Gut Pathogens 2019 11:7
  16. Helicobacter pylori is a Gram-negative bacterium that colonizes the gastric mucosa in humans. One of the main virulence factors of H. pylori is the cag pathogenicity island (cagPAI), which encodes a type 4-secret...

    Authors: Adolfo Román-Román, Verónica I. Martínez-Santos, Carlos A. Castañón-Sánchez, Alan J. Albañil-Muñoz, Paola González-Mendoza, Diana G. Soto-Flores, Dinorah N. Martínez-Carrillo and Gloria Fernández-Tilapa
    Citation: Gut Pathogens 2019 11:5
  17. Campylobacter jejuni secretes HtrA (high temperature requirement protein A), a serine protease that is involved in virulence. Here, we investigated the interaction of HtrA with the host protein occludin, a tight ...

    Authors: Aileen Harrer, Roland Bücker, Manja Boehm, Urszula Zarzecka, Nicole Tegtmeyer, Heinrich Sticht, Jörg D. Schulzke and Steffen Backert
    Citation: Gut Pathogens 2019 11:4
  18. Enterobacter hormaechei is an important emerging pathogen and a key member of the highly diverse Enterobacter cloacae complex. E. hormaechei strains can persist and spread in nosocomial environments, and often ex...

    Authors: Leigh G. Monahan, Matthew Z. DeMaere, Max L. Cummins, Steven P. Djordjevic, Piklu Roy Chowdhury and Aaron E. Darling
    Citation: Gut Pathogens 2019 11:3
  19. The emergence of colistin-resistant Enterobacteriaceae from human and animal sources is a public health concern as this antibiotic is considered to be the last line therapeutic option for infections caused by ...

    Authors: Zeinab Pishnian, Mehri Haeili and Adel Feizi
    Citation: Gut Pathogens 2019 11:2
  20. The onset of hepatocellular carcinoma (HCC) ranked fifth malignancies all over the world. Increasing evidences showed that the distribution of HCC was related to the incidence of chronic hepatitis B virus (HBV...

    Authors: Qisha Liu, Fan Li, Yaoyao Zhuang, Jian Xu, Jianwei Wang, Xuhua Mao, Yewei Zhang and Xingyin Liu
    Citation: Gut Pathogens 2019 11:1
  21. Salmonella enterica serotype Heidelberg is primarily a poultry adapted serotype of Salmonella that can also colonize other hosts and cause human disease. In this study, we compared the genomes of outbreak associa...

    Authors: Linto Antony, Melissa Behr, Donald Sockett, Dale Miskimins, Nicole Aulik, Jane Christopher-Hennings, Eric Nelson, Marc W. Allard and Joy Scaria
    Citation: Gut Pathogens 2018 10:53
  22. Antibiotic resistance is by far one of the most important health threats of our time. Only a global concerted effort of several disciplines based on the One-Health concept will help in slowing down this proces...

    Authors: Esther-Maria Antão, Szilvia Vincze, Regina Hanke, Lukas Klimmek, Katarzyna Suchecka, Antina Lübke-Becker and Lothar H. Wieler
    Citation: Gut Pathogens 2018 10:52
  23. Several pathogens have been debated to play a role in inflammatory bowel disease (IBD) including Crohn’s disease (CD). None of these pathogens have been investigated together in same clinical samples. We devel...

    Authors: Robert C. Sharp, Ebraheem S. Naser, Karel P. Alcedo, Ahmad Qasem, Latifa S. Abdelli and Saleh A. Naser
    Citation: Gut Pathogens 2018 10:51
  24. The intestinal microbiota plays a crucial role in the maintenance of gut homeostasis. Changes in crosstalk between the intestinal epithelial cells, immune cells and the microbiota are critically involved in th...

    Authors: Rogatien Charlet, Clovis Bortolus, Melissandre Barbet, Boualem Sendid and Samir Jawhara
    Citation: Gut Pathogens 2018 10:50
  25. The role of microbiota in Crohn’s disease (CD) is increasingly recognized. However, most of the reports are from Western populations. Considering the possible variation from other populations, the aim of this ...

    Authors: Mohammad I. El Mouzan, Harland S. Winter, Assad A. Assiri, Kirill S. Korolev, Ahmad A. Al Sarkhy, Scot E. Dowd, Mohammad A. Al Mofarreh and Rajita Menon
    Citation: Gut Pathogens 2018 10:49
  26. Vibrio parahaemolyticus is a causative agent of gastroenteritis. Most of the clinical isolates carry either tdh and/or trh genes which are considered as the major virulence genes of this pathogen. In this study, ...

    Authors: Jetnapang Kongrueng, Kanchana Srinitiwarawong, Mitsuaki Nishibuchi, Pimonsri Mittraparp-arthorn and Varaporn Vuddhakul
    Citation: Gut Pathogens 2018 10:48
  27. Shigella spp. are Gram-negative intracellular pathogenic bacteria belonging to the family Enterobacteriaceae and can cause bacterial dysentery, a severe diarrheal disease. The pathophysiological impact of the Gra...

    Authors: Laura Deutsch-Nagy, Péter Urbán, Zsuzsanna Tóth, Zoltán Bihari, Béla Kocsis, Csaba Fekete and Ferenc Kilár
    Citation: Gut Pathogens 2018 10:47
  28. As part of the effort to develop an enterotoxigenic Escherichia coli (ETEC) human challenge model for testing new heat-stable toxin (ST)-based vaccine candidates, a controlled human infection model study based on...

    Authors: Oda Barth Vedøy, Kurt Hanevik, Sunniva Todnem Sakkestad, Halvor Sommerfelt and Hans Steinsland
    Citation: Gut Pathogens 2018 10:46
  29. Cyclospora cayetanensis is a food-borne intestinal human parasite that causes outbreaks of diarrhea. There is a need for efficient laboratory methods for strain-level characterization to assist in outbreak invest...

    Authors: Yvonne Qvarnstrom, Yuping Wei-Pridgeon, Erik Van Roey, Subin Park, Ganesh Srinivasamoorthy, Fernanda S. Nascimento, Delynn M. Moss, Eldin Talundzic and Michael J. Arrowood
    Citation: Gut Pathogens 2018 10:45
  30. Reduced intestinal microbial diversity and bacterial imbalance (dysbiosis) are seen in studies of Crohn’s disease. As it is difficult to obtain biopsy samples before disease presentation, the earliest mucosal ...

    Authors: Claire L. O’Brien, Christopher J. Kiely and Paul Pavli
    Citation: Gut Pathogens 2018 10:44
  31. In the current study, nine foodborne “Locus of Enterocyte Effacement” (LEE)-negative Shiga toxin-producing Escherichia coli (STEC) strains were selected for whole genome sequencing and analysis for yet unknown ge...

    Authors: Nadja Saile, Elisabeth Schuh, Torsten Semmler, Inga Eichhorn, Lothar H. Wieler, Andreas Bauwens and Herbert Schmidt
    Citation: Gut Pathogens 2018 10:43
  32. Members of the species Kocuria rhizophila, belonging to the family Micrococcaceae in the phylum Actinobacteria, have been isolated from a wide variety of natural sources, such as soil, freshwater, fish gut, and c...

    Authors: Tae Woong Whon, Hyun Sik Kim and Jin-Woo Bae
    Citation: Gut Pathogens 2018 10:42
  33. There are a number of reports indicating correlation between outbreaks of campylobacteriosis and the consumption of raw vegetables. This study is a meta-analysis on the prevalence of Campylobacter in fresh vegeta...

    Authors: Hooriyeh Mohammadpour, Enayat Berizi, Saeid Hosseinzadeh, Majid Majlesi and Morteza Zare
    Citation: Gut Pathogens 2018 10:41
  34. Food products of animal origin brought into the EU from third countries, both legally and illegally, can harbor foodborne pathogens such as Salmonella enterica. In this study, we examined five S. enterica isolate...

    Authors: Anja Müller, Wiebke Jansen, Nils Th. Grabowski and Corinna Kehrenberg
    Citation: Gut Pathogens 2018 10:40
  35. Poultry remains one of the most important reservoir for zoonotic multidrug resistant pathogens. The global rise of antimicrobial resistance in Gram-negative bacteria is of reasonable concern and demands intens...

    Authors: Amira A. Moawad, Helmut Hotzel, Heinrich Neubauer, Ralf Ehricht, Stefan Monecke, Herbert Tomaso, Hafez M. Hafez, Uwe Roesler and Hosny El-Adawy
    Citation: Gut Pathogens 2018 10:39
  36. Shewanella algae has been recognized as an emerging human pathogen. However, not much is known about the mechanism of its pathogenesis and its adaptation to a special niche such as the hepatobiliary tract.

    Authors: Shu-Ying Tseng, Kwong-Chung Tung, Jan-Fang Cheng, Yi-Hsuan Lee, Zong-Yen Wu, Yu-Kai Hong, Shi-Yu Chen, Yao-Ting Huang and Po-Yu Liu
    Citation: Gut Pathogens 2018 10:38
  37. Culture-based diagnostic methods cannot achieve rapid and precise diagnoses for the identification of multiple diarrhoeal pathogens (DPs). A high-throughput multiplex genetic detection system (HMGS) was adapte...

    Authors: Shiwen Wang, Feng Yang, Dong Li, Juanxiu Qin, Weiwei Hou, Lian Jiang, Mimi Kong, Yong Wu, Yuchen Zhang, Fuju Zhao, Yi Fang, Yingxin Miao, Lingli Xu, Jie Chen, Zhijun Bao, Michal A. Olszewski…
    Citation: Gut Pathogens 2018 10:37
  38. Phylogenetic analysis of norovirus (NoV) is efficient for tracking NoV transmission. To determine the widespread NoV strains in Seoul, we conducted an extensive phylogenetic characterization of NoV-positives f...

    Authors: Young Eun Kim, Miok Song, Jaein Lee, Hyun Jung Seung, Eun-Young Kwon, Jinkyung Yu, Youngok Hwang, Taeho Yoon, Tae Jun Park and In Kyoung Lim
    Citation: Gut Pathogens 2018 10:36
  39. Diarrheagenic Escherichia coli (DEC) is one of the most important etiological agents of diarrheal diseases. In this study we investigated the prevalence, virulence gene profiles, antimicrobial resistance, and mol...

    Authors: Dan Li, Min Shen, Ying Xu, Chao Liu, Wen Wang, Jinyan Wu, Xianmei Luo, Xu Jia and Yongxin Ma
    Citation: Gut Pathogens 2018 10:35
  40. Salmonella enterica, serovar Enteritidis (S. Enteritidis), an important zoonotic foodborne pathogen, can affect the microbiota of the chicken intestine and cause many enteric diseases, such as acute gastroenterit...

    Authors: Liying Liu, Lili Lin, Linna Zheng, Hui Tang, Xinzhong Fan, Nianguo Xue, Min Li, Min Liu and Xianyao Li
    Citation: Gut Pathogens 2018 10:34
  41. Enterococci are commensal bacteria in the mammalian gastrointestinal tract which play an important role in the production of various fermented foods. Thus, certain enterococcal strains are commonly used as probio...

    Authors: Bailiang Li, Smith Etareri Evivie, Da Jin, Yueyue Meng, Na Li, Fenfen Yan, Guicheng Huo and Fei Liu
    Citation: Gut Pathogens 2018 10:32
  42. Staphylococcus aureus is one of the most prevalent pathogens and a causative agent of a variety of infections in humans and animals. A total of 640 samples were collected from healthy animals and patients from 20...

    Authors: Baoguang Liu, Huarun Sun, Yushan Pan, Yajun Zhai, Tian Cai, Xiaoling Yuan, Yanling Gao, Dandan He, Jianhua Liu, Li Yuan and Gongzheng Hu
    Citation: Gut Pathogens 2018 10:31
  43. Non-typhoidal Salmonella (NTS) infections caused primarily by S. Enteritidis and S. Typhimurium particularly in immunocompromised hosts have accounted for a large percentage of fatalities in developed nations. An...

    Authors: Shilpa Ray, Susmita Das, Pritam Kumar Panda and Mrutyunjay Suar
    Citation: Gut Pathogens 2018 10:30
  44. Over the years, genetic profiling of the gut microbiome of patients with colorectal cancer (CRC) using genome sequencing has suggested over-representation of several bacterial taxa. However, little is known ab...

    Authors: Siok-Fong Chin, Putri Intan Hafizah Megat Mohd Azlan, Luqman Mazlan and Hui-min Neoh
    Citation: Gut Pathogens 2018 10:29
  45. Gut colonization with vancomycin-resistant Enterococcus (VRE) is associated with poor outcomes. This study evaluated the impact of VRE colonization on subsequent acquisition of enteric pathogens.

    Authors: Jordan E. Axelrad, Benjamin Lebwohl, Edward Cuaresma, Ken Cadwell, Peter H. R. Green and Daniel E. Freedberg
    Citation: Gut Pathogens 2018 10:28
  46. Rotaviruses are the major causes of pediatric gastroenteritis worldwide. The genotypic distribution of rotavirus strains shows temporal and geographical fluctuations, and knowledge of the molecular epidemiolog...

    Authors: Su-Kyung Lee, Seoheui Choi, Seon-Hee Shin, Eun Jin Lee, Jungwon Hyun, Jae-Seok Kim and Hyun Soo Kim
    Citation: Gut Pathogens 2018 10:27