Articles
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Citation: Gut Pathogens 2016 8:35
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Comparative genomic analysis of Klebsiella pneumoniae subsp. pneumoniae KP617 and PittNDM01, NUHL24835, and ATCC BAA-2146 reveals unique evolutionary history of this strain
Klebsiella pneumoniae subsp. pneumoniae KP617 is a pathogenic strain that coproduces OXA-232 and NDM-1 carbapenemases. We sequenced the genome of KP617, which was isolated from the wou...
Citation: Gut Pathogens 2016 8:34 -
The IL-23/IL-22/IL-18 axis in murine Campylobacter jejuni infection
Human Campylobacter jejuni infections are worldwide on the rise. Information about the distinct molecular mechanisms underlying campylobacteriosis, however, are scarce. In the present study we investigated whethe...
Citation: Gut Pathogens 2016 8:21 -
Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model
Increased intestinal permeability and translocation of gut microbiota from the intestinal lumen to the systemic circulation predispose patients to various diseases and may be one of the main triggers thereof. ...
Citation: Gut Pathogens 2016 8:33 -
Complete genome sequence of Vibrio vulnificus FORC_017 isolated from a patient with a hemorrhagic rash after consuming raw dotted gizzard shad
Vibrio vulnificus, a resident in the human gut, is frequently found in seafood, causing food-borne illnesses including gastroenteritis and severe septicemia. While V. vulnificus has be...
Citation: Gut Pathogens 2016 8:22 -
RHB-104 triple antibiotics combination in culture is bactericidal and should be effective for treatment of Crohn’s disease associated with Mycobacterium paratuberculosis
Mycobacterium avium subspecies paratuberculosis (MAP) has been implicated as an etiological agent of Crohn’s disease (CD), a debilitating chronic inflammatory bowel disease. Clarithrom...
Citation: Gut Pathogens 2016 8:32 -
Prevalence and antibiotic resistance of bacterial pathogens isolated from childhood diarrhea in Beijing, China (2010–2014)
Diarrhea is one of the main causes of morbidity and mortality among children less than 5 years of age worldwide, and its causes vary by region. This study aimed to determine the etiologic spectrum, prevalent c...
Citation: Gut Pathogens 2016 8:31 -
Duck gut viral metagenome analysis captures snapshot of viral diversity
Ducks (Anas platyrhynchos) an economically important waterfowl for meat, eggs and feathers; is also a natural reservoir for influenza A viruses. The emergence of novel viruses is attributed to the status of co-ex...
Citation: Gut Pathogens 2016 8:30 -
Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA
The cell adhesion and tumor suppressor protein E-cadherin is an important factor in the establishment and maintenance of epithelial integrity. E-cadherin is a single transmembrane protein, which consists of an...
Citation: Gut Pathogens 2016 8:29 -
Prevalence, genotyping and risk factors of thermophilic Campylobacter spreading in organic turkey farms in Germany
The need for organic food of animal origin has increased rapidly in recent years. However, effects of organic animal husbandry on food safety have not been rigorously tested especially in meat turkey flocks. T...
Citation: Gut Pathogens 2016 8:28 -
The efficacy of thuricin CD, tigecycline, vancomycin, teicoplanin, rifampicin and nitazoxanide, independently and in paired combinations against Clostridium difficile biofilms and planktonic cells
Thuricin CD is a two-component antimicrobial, belonging to the recently designated sactibiotic subclass of bacteriocins. The aim of this study was to investigate the effects of thuricin CD, as well as the anti...
Citation: Gut Pathogens 2016 8:20 -
Optimized cultivation of Campylobacter concisus from gut mucosal biopsies in inflammatory bowel disease
Campylobacter concisus is a commensal of the human oral flora that has been linked to prolonged diarrhea and inflammatory bowel disease (IBD). It has been detected more often from inte...
Citation: Gut Pathogens 2016 8:27 -
Serotype epidemiology and multidrug resistance patterns of Salmonella enterica infecting humans in Italy
Salmonella enterica is the zoonotic agent most frequently responsible for foodborne infections in humans worldwide. In this work the presence of S. enterica was investigated in 734 uni...
Citation: Gut Pathogens 2016 8:26 -
Analysis of cultivable microbiota and diet intake pattern of the long-lived naked mole-rat
A variety of microbial communities exist throughout the human and animal body. Genetics, environmental factors and long-term dietary habit contribute to shaping the composition of the gut microbiota. For this ...
Citation: Gut Pathogens 2016 8:25 -
Inherent bacterial DNA contamination of extraction and sequencing reagents may affect interpretation of microbiota in low bacterial biomass samples
The advent and use of highly sensitive molecular biology techniques to explore the microbiota and microbiome in environmental and tissue samples have detected the presence of contaminating microbial DNA within...
Citation: Gut Pathogens 2016 8:24 -
Host, pathogen and environment: a bacterial gbpA gene expression study in response to magnesium environment and presence of prawn carapace and commercial chitin
Vibrio parahaemolyticus is a Gram-negative halophilic bacterium which is found largely in estuarine and coastal waters. The bacteria has been a main focus in gastro-intestinal infectio...
Citation: Gut Pathogens 2016 8:23 -
Examination of the effects of Campylobacter concisus zonula occludens toxin on intestinal epithelial cells and macrophages
Campylobacter concisus is a Gram-negative bacterium that is associated with inflammatory bowel disease (IBD). Some C. concisus strains carry zonula occludens toxin (zot) gene which has...
Citation: Gut Pathogens 2016 8:18 -
Genotyping and antibiotic resistance of thermophilic Campylobacter isolated from chicken and pig meat in Vietnam
Campylobacter species are recognized as the most common cause of foodborne bacterial gastroenteritis in humans. In this study nine Campylobacter strains isolated from chicken meat and ...
Citation: Gut Pathogens 2016 8:19 -
Global investigation of composition and interaction networks in gut microbiomes of individuals belonging to diverse geographies and age-groups
Factors like ethnicity, diet and age of an individual have been hypothesized to play a role in determining the makeup of gut microbiome. In order to investigate the gut microbiome structure as well as the inte...
Citation: Gut Pathogens 2016 8:17 -
The Salmonella pathogenicity island 13 contributes to pathogenesis in streptomycin pre-treated mice but not in day-old chickens
Salmonella enterica serovar Enteritidis (S. Enteritidis) is a human and animal pathogen that causes gastroenteritis characterized by inflammatory diarrhea and occasionally an invasive ...
Citation: Gut Pathogens 2016 8:16 -
Host, pathogen and the environment: the case of Macrobrachium rosenbergii, Vibrio parahaemolyticus and magnesium
Macrobrachium rosenbergii is well-known as the giant freshwater prawn, and is a commercially significant source of seafood. Its production can be affected by various bacterial contaminati...
Citation: Gut Pathogens 2016 8:15 -
Draft genome sequence of non-shiga toxin-producing Escherichia coli O157 NCCP15738
The non-shiga toxin-producing Escherichia coli (non-STEC) O157 is a pathogenic strain that cause diarrhea but does not cause hemolytic-uremic syndrome, or hemorrhagic colitis. Here, we present the 5-Mb draft geno...
Citation: Gut Pathogens 2016 8:13 -
Genotyping of Salmonella Typhi using 8-loci multi locus VNTR analysis
Typhoid fever has caused severe epidemics in many Asian and African countries. The early detection of outbreaks and their sources may promote the prevention and control of typhoid fever, for which effective an...
Citation: Gut Pathogens 2016 8:14 -
Complete genome sequence of Peptoclostridium difficile strain Z31
Peptoclostridium (Clostridium) difficile is a spore-forming bacterium responsible for nosocomial infections in humans. It is recognized as an important agent of diarrhea and colitis in...
Citation: Gut Pathogens 2016 8:11 -
Helicobacter pylori plasticity region genes are associated with the gastroduodenal diseases manifestation in India
Almost all Helicobacter pylori infected person develop gastritis and severe gastritis is supposed to be the denominator of peptic ulcer diseases, which may lead to gastric cancer. However, it is still an enigma w...
Citation: Gut Pathogens 2016 8:10 -
The isolation and molecular characterization of Mycobacterium avium subsp. paratuberculosis in Shandong province, China
Mycobacterium avium subspecies paratuberculosis (Map) causes Johne’s disease in domestic and wild ruminants. It has been a debate that whether Map can cause Crohn’s disease in human. T...
Citation: Gut Pathogens 2016 8:9 -
Systematic review of time trends in the prevalence of Helicobacter pylori infection in China and the USA
It has been suggested that the prevalence of Helicobacter pylori infection has stabilized in the USA and is decreasing in China. We conducted a systematic literature analysis to test this hypothesis. PubMed and E...
Citation: Gut Pathogens 2016 8:8 -
Oxidative stress due to Mycobacterium avium subspecies paratuberculosis (MAP) infection upregulates selenium-dependent GPx activity
This study was designed to determine the relationship between Mycobacterium avium subspecies paratuberculosis (MAP) infection and selenium-dependent glutathione peroxidase (GPx) activity, in the blood of humans a...
Citation: Gut Pathogens 2016 8:12 -
Genome sequence of Escherichia coli NCCP15653, a group D strain isolated from a diarrhea patient
Pathogenic strains in Escherichia coli can be divided into several pathotypes according to their virulence features. Among them, uropathogenic E. coli causes most of the urinary tract infections and has a genotyp...
Citation: Gut Pathogens 2016 8:7 -
Genomic characterization and assessment of the virulence and antibiotic resistance of the novel species Paenibacillus sp. strain VT-400, a potentially pathogenic bacterium in the oral cavity of patients with hematological malignancies
Paenibacillus sp. strain VT-400, a novel spore-forming bacterium, was isolated from patients with hematological malignancies.
Citation: Gut Pathogens 2016 8:6 -
De Novo sphingolipid synthesis is essential for Salmonella-induced autophagy and human beta-defensin 2 expression in intestinal epithelial cells
Sphingolipids are important for innate immune response to eliminate infected pathogens and involved in autophagy. On the other hand, nucleotide-binding oligomerization domain-containing protein 2 (NOD2) served...
Citation: Gut Pathogens 2016 8:5 -
Surface antigens contribute differently to the pathophysiological features in serotype K1 and K2 Klebsiella pneumoniae strains isolated from liver abscesses
The virulence role of surface antigens in a single serotype of Klebsiella pneumoniae strain have been studied, but little is known about whether their contribution will vary with serotype.
Citation: Gut Pathogens 2016 8:4 -
Whole genome sequencing of “Faecalibaculum rodentium” ALO17, isolated from C57BL/6J laboratory mouse feces
Intestinal microorganisms affect host physiology, including ageing. Given the difficulty in controlling for human studies of the gut microbiome, mouse models provide an alternative avenue to study such relatio...
Citation: Gut Pathogens 2016 8:3 -
Increased dosage of infliximab is a potential cause of Pneumocystis carinii pneumonia
Pneumocystis carinii pneumonia occasionally appears in immunodeficient patients. While several reports have shown that Pneumocystis carinii pneumonia occurred in the early phase of sta...
Citation: Gut Pathogens 2016 8:2 -
Helicobacter pylori strains harboring babA2 from Indian sub population are associated with increased virulence in ex vivo study
The babA2 gene along with the cagA and vacA of Helicobacter pylori has been considered as a risk factor for the disease outcome in certain populations. This study was aimed to understand the role of babA2 of H. p...
Citation: Gut Pathogens 2016 8:1 -
Lactobacilli with probiotic potential in the prairie vole (Microtus ochrogaster)
Recent research suggests integration of the intestinal microbiota in gut-brain communication which could lead to new approaches to treat neurological disorders. The highly social prairie voles are an excellen...
Citation: Gut Pathogens 2015 7:35 -
Non-Typhoidal Salmonella in poultry meat and diarrhoeic patients: prevalence, antibiogram, virulotyping, molecular detection and sequencing of class I integrons in multidrug resistant strains
The worldwide increase of food-borne infections with antibiotic resistant pathogens constitutes a major public health problem. Therefore, this study aimed to determine the prevalence, antibiogram, virulence ge...
Citation: Gut Pathogens 2015 7:34 -
Comparison of a novel chemiluminescent based algorithm to three algorithmic approaches for the laboratory diagnosis of Clostridium difficile infection
Rapid commercial assays, including nucleic acid amplification tests and immunoassays for Clostridium. difficile toxins, have replaced the use of older assays. They are included in a two-step algorithm diagnosis, ...
Citation: Gut Pathogens 2015 7:33 -
Development of gut inflammation in mice colonized with mucosa-associated bacteria from patients with ulcerative colitis
Disturbances in the intestinal microbial community (i.e. dysbiosis) or presence of the microbes with deleterious effects on colonic mucosa has been linked to the pathogenesis of inflammatory bowel diseases. Ho...
Citation: Gut Pathogens 2015 7:32 -
Core 2 mucin-type O-glycan inhibits EPEC or EHEC O157:H7 invasion into HT-29 epithelial cells
How host cell glycosylation affects EPEC or EHEC O157:H7 invasion is unclear. This study investigated whether and how O-glycans were involved in EPEC or EHEC O157:H7 invasion into HT-29 cells.
Citation: Gut Pathogens 2015 7:31 -
Description of Campylobacter jejuni Bf, an atypical aero-tolerant strain
Campylobacter jejuni is a leading cause of bacterial enteritis worldwide. This microaerophilic bacterium can survive in aerobic environments, suggesting it has protective mechanisms ag...
Citation: Gut Pathogens 2015 7:30 -
Animal models to study acute and chronic intestinal inflammation in mammals
Acute and chronic inflammatory diseases of the intestine impart a significant and negative impact on the health and well-being of human and non-human mammalian animals. Understanding the underlying mechanisms ...
Citation: Gut Pathogens 2015 7:29 -
Survey of small intestinal and systemic immune responses following murine Arcobacter butzleri infection
Arcobacter (A.) butzleri has been described as causative agent for sporadic cases of human gastroenteritis with abdominal pain and acute or prolonged watery diarrhea. In vitro studies ...
Citation: Gut Pathogens 2015 7:28 -
Streptococcus bovis infectious endocarditis and occult gastrointestinal neoplasia: experience with 25 consecutive patients treated surgically
To assess the prevalence of gastrointestinal neoplasia in patients with Streptococcus bovis infectious endocarditis we performed a retrospective cohort analysis of all episodes of S. bovis infectious endocarditis...
Citation: Gut Pathogens 2015 7:27 -
Helicobacter pylori virulence genes in the five largest islands of Indonesia
It remains unclear whether the low incidence of gastric cancer in Indonesia is due to low infection rates only or is also related to low Helicobacter pylori pathogenicity. We collected H. pylori strains from the ...
Citation: Gut Pathogens 2015 7:26 -
Specific detection of OCT4 isoforms in inflammatory bowel disease
Developmentally early cells are mobilized into peripheral blood in Crohn’s disease (CD) patients. OCT4, is considered to be important in sustaining the pluripotency of stem cells. OCT4 splicing variants are diffe...
Citation: Gut Pathogens 2015 7:25 -
The O-antigen negative ∆wbaV mutant of Salmonella enterica serovar Enteritidis shows adaptive resistance to antimicrobial peptides and elicits colitis in streptomycin pretreated mouse model
Salmonella enterica serovar Enteritidis, the most common cause of human gastroenteritis, employs several virulence factors including lipopolysaccharide (LPS) for infection and establis...
Citation: Gut Pathogens 2015 7:24 -
High dietary zinc supplementation increases the occurrence of tetracycline and sulfonamide resistance genes in the intestine of weaned pigs
Dietary zinc oxide is used in pig nutrition to combat post weaning diarrhoea. Recent data suggests that high doses (2.5 g/kg feed) increase the bacterial antibiotic resistance development in weaned pigs. There...
Citation: Gut Pathogens 2015 7:23 -
Interaction of caffeine with the SOS response pathway in Escherichia coli
Previous studies have highlighted the antimicrobial activity of caffeine, both individually and in combination with other compounds. A proposed mechanism for caffeine’s antimicrobial effects is inhibition of b...
Citation: Gut Pathogens 2015 7:21 -
Genome architecture of Lactobacillus plantarum PS128, a probiotic strain with potential immunomodulatory activity
Clinical and preclinical observations indicate that Lactobacillus plantarum has anti-inflammatory activity and may regulate the immune responses of its hosts when ingested. Recently, modification of teichoic acid...
Citation: Gut Pathogens 2015 7:22
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- ISSN: 1757-4749 (electronic)