Vandevijvere S, Chow CC, Hall KD, Umali E, Swinburn BA. Increased food energy supply as a major driver of the obesity epidemic: a global analysis. Bull World Health Organ. 2015;93:446–56.
Article
PubMed
PubMed Central
Google Scholar
World Health Organization (WHO). World Health Organization (WHO). 2020. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
NCD-Risk Factor Collaboration. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377–96.
Article
Google Scholar
El-Kebbi IM, Bidikian NH, Hneiny L, Nasrallah MP. Epidemiology of type 2 diabetes in the Middle East and North Africa: challenges and call for action. World J Diabetes. 2021;12:1401–25.
Article
PubMed
PubMed Central
Google Scholar
Scheithauer TPM, Rampanelli E, Nieuwdorp M, Vallance BA, Verchere CB, van Raalte DH, et al. Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes. Front Immunol. 2020;11:1–29.
Article
CAS
Google Scholar
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 2011;11:98–107. https://doi.org/10.1038/nri2925.
Article
CAS
PubMed
Google Scholar
Bedhiafi T, Charradi K, Ben Azaiz M, Mahmoudi M, Msakni I, Jebari K, et al. Supplementation of grape seed and skin extract to orlistat therapy prevents high-fat diet-induced murine spleen lipotoxicity. Appl Physiol Nutr Metab Physiol Appl Nutr Metab. 2018. https://doi.org/10.1139/apnm-2017-0743.
Article
Google Scholar
Manor O, Dai CL, Kornilov SA, Smith B, Price ND, Lovejoy JC, et al. Health and disease markers correlate with gut microbiome composition across thousands of people. Nat Commun. 2020;11:1–12. https://doi.org/10.1038/s41467-020-18871-1.
Article
CAS
Google Scholar
Zhao L. The gut microbiota and obesity: from correlation to causality. Nat Rev Microbiol. 2013;11:639–47. https://doi.org/10.1038/nrmicro3089.
Article
CAS
PubMed
Google Scholar
Nishida A, Inoue R, Inatomi O, Bamba S, Naito Y, Andoh A. Gut microbiota in the pathogenesis of inflammatory bowel disease. Clin J Gastroenterol. 2018;11:1–10.
Article
PubMed
Google Scholar
Iyengar NM, Gucalp A, Dannenberg AJ, Hudis CA. Obesity and cancer mechanisms: tumor microenvironment and inflammation. J Clin Oncol. 2016;34:4270–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boulangé CL, Neves AL, Chilloux J, Nicholson JK, Dumas ME. Impact of the gut microbiota on inflammation, obesity, and metabolic disease. Genome Med. 2016;8:1–12. https://doi.org/10.1186/s13073-016-0303-2.
Article
CAS
Google Scholar
Cani PD, Bibiloni R, Knauf C, Neyrinck AM, Delzenne NM. Changes in gut microbiota control metabolic diet–induced obesity and diabetes in mice. Diabetes. 2008;57:1470–81.
Article
CAS
PubMed
Google Scholar
Fan Y, Pedersen O. Gut microbiota in human metabolic health and disease. Nat Rev Microbiol. 2021;19:55–71. https://doi.org/10.1038/s41579-020-0433-9.
Article
CAS
PubMed
Google Scholar
Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med. 2017;23:107–13. https://doi.org/10.1038/nm.4236.
Article
CAS
PubMed
Google Scholar
Dao MC, Everard A, Aron-Wisnewsky J, Sokolovska N, Prifti E, Verger EO, et al. Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut. 2016;65:426–36.
Article
CAS
PubMed
Google Scholar
Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes. 2007;56:1761–72.
Article
CAS
PubMed
Google Scholar
Mocanu V, Zhang Z, Deehan EC, Kao DH, Hotte N, Karmali S, et al. Fecal microbial transplantation and fiber supplementation in patients with severe obesity and metabolic syndrome: a randomized double-blind, placebo-controlled phase 2 trial. Nat Med. 2021;27:1272–9. https://doi.org/10.1038/s41591-021-01399-2.
Article
CAS
PubMed
Google Scholar
Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, Mende DR, et al. Enterotypes of the human gut microbiome. Nature. 2011;473:174–80. https://doi.org/10.1038/nature09944.
Article
CAS
PubMed
PubMed Central
Google Scholar
Le Barz M, Anhê FF, Varin TV, Desjardins Y, Levy E, Roy D, et al. Probiotics as complementary treatment for metabolic disorders. Diabetes Metab J. 2015;39:291–303.
Article
PubMed
PubMed Central
Google Scholar
Cotillard A, Kennedy SP, Kong LC, Prifti E, Pons N, Le Chatelier E, et al. Dietary intervention impact on gut microbial gene richness. Nature 2013;500:585–8. http://www.nature.com/articles/nature12480
Gibson GR, Hutkins R, Sanders ME, Prescott SL, Reimer RA, Salminen SJ, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol. 2017;14:491–502. https://doi.org/10.1038/nrgastro.2017.75.
Article
PubMed
Google Scholar
Anhê FF, Varin TV, Le Barz M, Desjardins Y, Levy E, Roy D, et al. Gut microbiota dysbiosis in obesity-linked metabolic diseases and prebiotic potential of polyphenol-rich extracts. Curr Obes Rep. 2015;4:389–400.
Article
PubMed
Google Scholar
Alves-Santos AM, Sugizaki CSA, Lima GC, Naves MMV. Prebiotic effect of dietary polyphenols: a systematic review. J Funct Foods. 2020;74:104169. https://doi.org/10.1016/j.jff.2020.104169.
Article
CAS
Google Scholar
Dudonné S, Varin TV, Forato Anhê F, Dubé P, Roy D, Pilon G, et al. Modulatory effects of a cranberry extract co-supplementation with Bacillus subtilis CU1 probiotic on phenolic compounds bioavailability and gut microbiota composition in high-fat diet-fed mice. PharmaNutrition. 2015;3:89–100. https://doi.org/10.1016/j.phanu.2015.04.002.
Article
CAS
Google Scholar
Cheah KY, Bastian SEP, Acott TMV, Abimosleh SM, Lymn KA, Howarth GS. Grape seed extract reduces the severity of selected disease markers in the proximal colon of dextran sulphate sodium-induced colitis in rats. Dig Dis Sci. 2013;58:970–7.
Article
PubMed
Google Scholar
Charradi K, Mahmoudi M, Bedhia T, Kadri S. ScienceDirect Dietary supplementation of grape seed and skin flour mitigates brain oxidative damage induced by a high-fat diet in rat: gender dependency. Biomed Pharmacother. 2017;87:519–26.
Article
CAS
PubMed
Google Scholar
Mahmoudi M, Charradi K, Limam F, Aouani E. Grape seed and skin extract as an adjunct to xenical therapy reduces obesity, brain lipotoxicity and oxidative stress in high fat diet fed rats. Obes Res Clin Pract. 2018;12:115–26.
Article
PubMed
Google Scholar
Kadri S, El Ayed M, Cosette P, Jouenne T, Elkhaoui S, Zekri S, et al. Neuroprotective effect of grape seed extract on brain ischemia: a proteomic approach. Metab Brain Dis. 2019;34:889–907.
Article
CAS
PubMed
Google Scholar
Ke J, An Y, Cao B, Lang J, Wu N, Zhao D. Orlistat-induced gut microbiota modification in obese mice. Evid Based Complement Altern Med. 2020;2020:1–9.
Article
Google Scholar
Orlistat (marketed as Alli and Xenical) Information | FDA [Internet]. [cited 2022 Feb 23]. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/orlistat-marketed-alli-and-xenical-information
Filippatos TD, Derdemezis CS, Gazi IF, Nakou ES, Mikhailidis DP, Elisaf MS. Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf. 2008;31:53–65.
Article
CAS
PubMed
Google Scholar
Mokni M, Hamlaoui S, Kadri S, Limam F, Amri M, Marzouki L, et al. Efficacy of grape seed and skin extract against doxorubicin-induced oxidative stress in rat liver. Pak J Pharm Sci. 2015;28:1971–8.
CAS
PubMed
Google Scholar
Escudié F, Auer L, Bernard M, Mariadassou M, Cauquil L, Vidal K, et al. FROGS: find, rapidly, OTUs with galaxy solution. Bioinformatics (Oxford, England). 2018;34:1287–94.
Article
CAS
Google Scholar
Volant S, Lechat P, Woringer P, Motreff L, Campagne P, Malabat C, et al. Open Access SHAMAN : a user-friendly website for metataxonomic analysis from raw reads to statistical analysis. BMC Bioinform. 2020. https://doi.org/10.1186/s12859-020-03666-4.
Article
Google Scholar
Janda MW. The genus streptococcus—part i: emerging pathogens in the “Pyogenic Cocci” and the “Streptococcus bovis. Groups Clin Microbiol Newslett. 2014;36(20):157–66.
Article
Google Scholar
Jiao X, Wang Y, Lin Y, Lang Y, Li E, Zhang X, et al. Blueberry polyphenols extract as a potential prebiotic with anti-obesity effects on C57BL/6J mice by modulating the gut microbiota. J Nutr Biochem. 2019;64:88–100.
Article
CAS
PubMed
Google Scholar
Ke X, Walker A, Haange SB. Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice. Mol Metab. 2019;22:96–109.
Article
CAS
PubMed
PubMed Central
Google Scholar
Collins B, Hoffman J, Martinez K, Grace M, Lila MA, Cockrell C, et al. A polyphenol-rich fraction obtained from table grapes decreases adiposity, insulin resistance and markers of inflammation and impacts gut microbiota in high-fat-fed mice. J Nutr Biochem. 2016;31:150–65. https://doi.org/10.1016/j.jnutbio.2015.12.021.
Article
CAS
PubMed
PubMed Central
Google Scholar
Peters BA, Shapiro JA, Church TR, Miller G, Trinh-Shevrin C, Yuen E, et al. A taxonomic signature of obesity in a large study of American adults. Sci Rep. 2018. https://doi.org/10.1038/s41598-018-28126-1.
Article
PubMed
PubMed Central
Google Scholar
Zeng H, Ishaq SL, Zhao FQ, Wright ADG. Colonic inflammation accompanies an increase of β-catenin signaling and Lachnospiraceae/Streptococcaceae bacteria in the hind gut of high-fat diet-fed mice. J Nutr Biochem. 2016;35:30–6.
Article
CAS
PubMed
Google Scholar
Fei N, Zhao L. An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice. ISME J. 2013;7:880–4.
Article
CAS
PubMed
Google Scholar
Boer CG, Radjabzadeh D, Medina-Gomez C, Garmaeva S, Schiphof D, Arp P, et al. Intestinal microbiome composition and its relation to joint pain and inflammation. Nat Commun. 2019;10:4881.
Article
PubMed
PubMed Central
CAS
Google Scholar
Takewaki D, Yamamura T. Gut microbiome dysbiosis shapes disease course in the different stages of multiple sclerosis. Clin Exp Neuroimmunol. 2021;12:87–8.
Article
Google Scholar
Dekker JP, Lau AF. An update on the Streptococcus bovis group: classification, identification, disease associations. J Clin Microbiol. 2014;54(7):1694–9.
Article
Google Scholar
Pasquereau-Kotula E, Martins M, Aymeric L, Dramsi S. Significance of Streptococcus gallolyticus subsp. gallolyticus association with colorectal cancer. Front Microbiol. 2018;9:614.
Article
PubMed
PubMed Central
Google Scholar
Gu S, Chen Y, Wu Z, Chen Y, Gao H, Lv L, et al. Alterations of the gut microbiota in patients with coronavirus disease 2019 or H1N1 influenza. Clin Infect Dis. 2020;71(10):2669–78.
Article
CAS
PubMed
Google Scholar
Nguyen TLA, Vieira-Silva S, Liston A, Raes J. How informative is the mouse for human gut microbiota research? Dis Models Mech 2015;8:1–16. https://journals.biologists.com/dmm/article/8/1/1/3621/How-informative-is-the-mouse-for-human-gut
Nguyen QV, Chong LC, Hor Y-Y, Lew L-C, Rather IA, Choi S-B. Role of probiotics in the management of COVID-19: a computational perspective. Nutrients. 2022;14:274.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zuo T, Liu Q, Zhang F, Lui GC-Y, Tso EYK, Yeoh YK, et al. Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut. 70:276.
Augusti PR, Conterato GMM, Denardin CC. Bioactivity, bioavailability, and gut microbiota transformations of dietary phenolic compounds: implications for COVID-19. J Nutr Biochem. 2021;97:108787.
Article
CAS
PubMed
PubMed Central
Google Scholar
Santos J, Ribeiro M, Gambero A. The impact of polyphenols-based diet on the inflammatory profile in COVID-19 elderly and obese patients. Integr Physiol. 2021;11:612268.
Google Scholar
Clavel T, Desmarchelier C, Haller D, Gérard P, Rohn S, Lepage P. Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance. Gut Microbes. 2014;5:544–51.
Article
PubMed
Google Scholar
Gallardo-Becerra L, Cornejo-Granados F, García-López R. Metatranscriptomic analysis to define the Secrebiome, and 16S rRNA profiling of the gut microbiome in obesity and metabolic syndrome of Mexican children. Microb Cell Fact. 2020;19:1–18.
Article
CAS
Google Scholar
Martínez I, Muller CE, Walter J. Long-term temporal analysis of the human fecal microbiota revealed a stable core of dominant bacterial species. PLoS ONE. 2013;8:e69621.
Article
PubMed
PubMed Central
CAS
Google Scholar
Bangsgaard Bendtsen KM, Krych L, Sørensen DB, Pang W, Nielsen DS, Josefsen K. Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse. PLoS ONE. 2012;7:46231.
Article
CAS
Google Scholar
Zheng P, Zeng B, Liu M, Chen J, Pan J, Han Y, et al. The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice. Sci Adv. 2019;5(2):eaau8317.
Article
CAS
PubMed
PubMed Central
Google Scholar
Painold A, Mörkl S, Kashofer K, Halwachs B, Dalkner N, Bengesser S, et al. A step ahead: exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode. Bipolar Disord. 2019;21:40–9.
Article
CAS
PubMed
Google Scholar
Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature. 2012;490:60.
Article
CAS
Google Scholar
Kim KA, Gu W, Lee IA. High fat diet induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway. PLoS ONE. 2012;7:e47713.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rettedal E, Vilain S, Lindblom S, Lehnert K, Scofield C, George S, et al. Alteration of the ileal microbiota of weanling piglets by the growth-promoting antibiotic chlortetracycline. Appl Environ Microbiol. 2019;75:5489–95.
Article
CAS
Google Scholar
Kang X, Zhan L, Lu X, Song J, Zhong Y, Wang Y. Characteristics of gastric microbiota in GK rats with spontaneous diabetes: a comparative study. Diabetes Metab Syndr Obes. 2020;13:1435–47.
Article
CAS
PubMed
PubMed Central
Google Scholar
Armougom F, Henry M, Vialettes B, Raccah D, Raoult D. Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS ONE. 2009;4:1–8.
Article
CAS
Google Scholar
Mukherjee A, Lordan C, Ross RP, Cotter PD. Gut microbes from the phylogenetically diverse genus Eubacterium and their various contributions to gut health. Gut Microbes. 2020;12:1802866.
Article
PubMed
PubMed Central
CAS
Google Scholar
Wang S, Huang M, You X, Zhao J, Chen L, Wang L, et al. Gut microbiota mediates the anti-obesity effect of calorie restriction in mice. Sci Rep. 2018;8:2–15. https://doi.org/10.1038/s41598-018-31353-1.
Article
CAS
Google Scholar
Mazier W, Le Corf K, Martinez C, Tudela H, Kissi D, Kropp C, et al. A new strain of Christensenella minuta as a potential biotherapy for obesity and associated metabolic diseases. Cells. 2021;10:823.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ye J, Zhao Y, Chen X, Zhou H, Yang Y, Zhang X, et al. Pu-erh tea ameliorates obesity and modulates gut microbiota in high fat diet fed mice. Food Res Int. 2021;144:0963–9969.
Article
CAS
Google Scholar
Corcoran BM, Stanton C, Fitzgerald GF, Ross RP, P Ross PaulRoss CR. Growth of probiotic lactobacilli in the presence of oleic acid enhances subsequent survival in gastric juice. http://mic.sgmjournals.org
Lee SY, Yu J, Ahn KM, Kim KW, Shin YH, Lee KS, et al. Additive effect between IL-13 polymorphism and cesarean section delivery/prenatal antibiotics use on atopic dermatitis: a birth cohort study (COCOA). PLoS ONE. 2014;9:e96603.
Article
PubMed
PubMed Central
CAS
Google Scholar
Jang HR, Park HJ, Kang D, Chung H, Nam MH, Lee Y, et al. A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption. Exp Mol Med. 2019;51:1–14.
PubMed
Google Scholar
Plamada D, Cristian VD. Polyphenols-gut microbiota interrelationship: a transition to a new generation of prebiotics. Nutrients. 2021. https://doi.org/10.3390/nu14010137.
Article
PubMed
PubMed Central
Google Scholar
Daisley BA, Koenig D, Engelbrecht K, Doney L, Hards K, Al KF, et al. Emerging connections between gut microbiome bioenergetics and chronic metabolic diseases. Cell Rep. 2021. https://doi.org/10.1016/j.celrep.2021.110087.
Article
PubMed
Google Scholar
Stadlbauer V, Engertsberger L, Komarova I, Feldbacher N, Leber B, Pichler G, et al. Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study. BMC Geriatr. 2020;20:1–13. https://doi.org/10.1186/s12877-020-01644-2.
Article
CAS
Google Scholar
Lee SM, Han HW, Yim SY. Beneficial effects of soy milk and fiber on high cholesterol diet-induced alteration of gut microbiota and inflammatory gene expression in rats. Food Funct. 2015;6:492–500.
Article
CAS
PubMed
Google Scholar
Kelly TN, Bazzano LA, Ajami NJ, He H, Zhao J, Petrosino JF, et al. Gut microbiome associates with lifetime cardiovascular disease risk profile among Bogalusa heart study participants. Circ Res. 2016;119:956–64. https://doi.org/10.1161/CIRCRESAHA.116.309219.
Article
CAS
PubMed
PubMed Central
Google Scholar
Forbes JD, Van Domselaar G, Bernstein CN. The gut microbiota in immune-mediated inflammatory diseases. Front Microbiol. 2016;7:1081.
Article
PubMed
PubMed Central
Google Scholar
Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, et al. Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects. J Gastroenterol. 2019;54:53–63.
Article
PubMed
Google Scholar
Chung Y, Ryu Y, An BC, Yoon YS, Choi O, Kim TY, et al. A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota. Microbiome. 2021;9:1–17. https://doi.org/10.1186/s40168-021-01071-4.
Article
CAS
Google Scholar
Charradi K, Elkahoui S, Karkouch I, Limam F, Ben Hassine F, El May MV, et al. Protective effect of grape seed and skin extract against high-fat diet-induced liver steatosis and zinc depletion in rat. Dig Dis Sci. 2014;59(8):1768–78.
Article
PubMed
Google Scholar
Humbert G, Guingamp MF, Linden G. Method for the measurement of lipase activity in milk. J Dairy Res. 1997;64:465–9.
Article
CAS
PubMed
Google Scholar