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  1. Innovative research highlighted the probable connection between autism spectrum disorder (ASD) and gut microbiota as many autistic individuals have gastrointestinal problems as co-morbidities. This review emph...

    Authors: Laila Al-Ayadhi, Naima Zayed, Ramesa Shafi Bhat, Nadine M. S. Moubayed, May N. Al-Muammar and Afaf El-Ansary
    Citation: Gut Pathogens 2021 13:54
  2. To comprehensively analyze the risk factors, clinical characteristics, outcomes, and prognostic factors of Cytomegalovirus (CMV) enteritis.

    Authors: Pai-Jui Yeh, Cheng-Tang Chiu, Ming-Wei Lai, Ren-Chin Wu, Chien-Ming Chen, Chia-Jung Kuo, Jun-Te Hsu, Ming-Yao Su, Wei-Pin Lin, Tsung-Hsing Chen and Puo-Hsien Le
    Citation: Gut Pathogens 2021 13:53
  3. Dysregulated gut microbiota is one of major pathogenic factors in the development of colitis. Dock2 acts as a guanine nucleotide exchange factor (GEF) and activates small G protein RAC1. Our previous study sho...

    Authors: Yuan Xie, Jun Chen, Bing Wu, Tiansheng He, Lu Xie and Zhiping Liu
    Citation: Gut Pathogens 2021 13:52
  4. Anastomotic failure causes morbidity and mortality even in technically correct anastomoses. Initial leaks must be prevented by mucosal reapproximation across the anastomosis. Healing is a concerted effort betw...

    Authors: Emilie E. Vomhof-DeKrey, Allie Stover and Marc D. Basson
    Citation: Gut Pathogens 2021 13:51
  5. A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the deve...

    Authors: A. L. Cunningham, J. W. Stephens and D. A. Harris
    Citation: Gut Pathogens 2021 13:50
  6. Campylobacter jejuni (C. jejuni) is accountable for more than 400 million cases of gastroenteritis each year and is listed as a high-priority gut pathogen by the World Health Organization (WHO). Although the acut...

    Authors: Chandan Gorain, Afruja Khan, Ankita Singh, Samiran Mondal and Amirul Islam Mallick
    Citation: Gut Pathogens 2021 13:48
  7. In the wake of emergence of antimicrobial resistance, bioactive phytochemical compounds are proving to be important therapeutic agents. The present study envisaged in silico molecular docking as well as in vit...

    Authors: Padikkamannil Abishad, Pollumahanti Niveditha, Varsha Unni, Jess Vergis, Nitin Vasantrao Kurkure, Sandeep Chaudhari, Deepak Bhiwa Rawool and Sukhadeo Baliram Barbuddhe
    Citation: Gut Pathogens 2021 13:46
  8. The prevalence of antimicrobial resistance (AMR) among Gram-negative bacteria is alarmingly high. Reintroduction of colistin as last resort treatment in the infections caused by drug-resistant Gram-negative ba...

    Authors: Deepa Karki, Binod Dhungel, Srijana Bhandari, Anil Kunwar, Prabhu Raj Joshi, Basudha Shrestha, Komal Raj Rijal, Prakash Ghimire and Megha Raj Banjara
    Citation: Gut Pathogens 2021 13:45
  9. Intestinal epithelial cells are challenged by mycotoxins and many bacterial pathogens. It was previously shown that the mycotoxin deoxynivalenol (DON) as well as Campylobacter (C.) jejuni have a negative impact o...

    Authors: Daniel Ruhnau, Claudia Hess, Barbara Doupovec, Bertrand Grenier, Dian Schatzmayr, Michael Hess and Wageha Awad
    Citation: Gut Pathogens 2021 13:44
  10. Amoxicillin-resistant H. pylori strains are increasing worldwide. To explore the potential resistance mechanisms involved, the 3D structure modeling and access tunnel prediction for penicillin-binding proteins (P...

    Authors: Bahareh Attaran, Najmeh Salehi, Bahareh Ghadiri, Maryam Esmaeili, Shadi Kalateh, Mohammad Tashakoripour, Mahmoud Eshagh Hosseini and Marjan Mohammadi
    Citation: Gut Pathogens 2021 13:43
  11. Campylobacter jejuni (C. jejuni) infections are of increasing importance worldwide. As a typical mucosal pathogen, the interaction of C. jejuni with mucins is a prominent step in the colonisation of mucosal surfa...

    Authors: De Xi, Lukas Hofmann, Thomas Alter, Ralf Einspanier, Stefan Bereswill, Markus M. Heimesaat, Greta Gölz and Soroush Sharbati
    Citation: Gut Pathogens 2021 13:42
  12. Lentibacillus species are gram variable aerobic bacteria that live primarily in halophilic environments. Previous reports have shown that bacteria belonging to this species are primarily isolated from salty envir...

    Authors: Seung Woo Ahn, Se Hee Lee, Hong-Seok Son, Seong Woon Roh and Yoon-E Choi
    Citation: Gut Pathogens 2021 13:41
  13. Two different types of hypervirulent K. pneumoniae (HvKp), the MLST-11 and serotype K1/K2 strains, have been frequently described in recent studies. Although these two types of strains were described to be HvKp, ...

    Authors: Tsui-Chin Wang, Jung-Chung Lin, Jen-Chang Chang, Ya-Wen Hiaso, Ching-Hsun Wang, Sheng‑Kung Chiu, Chang-Phone Fung, Feng-Yee Chang and L. Kristopher Siu
    Citation: Gut Pathogens 2021 13:40
  14. There are geographic variations in the genotypes of Helicobacter pylori (H. pylori) cagA, vacA, iceA, oipA and dupA. The aim of the study was to investigate the distribution of these genotypes among H. pylori str...

    Authors: Zhijing Xue, Hong Yang, Dongxing Su, Xiangfeng Song, Xin Deng, Changhong Yu, Chunhua Sun, Lihua He, Yuanhai You, Yanan Gong, Dongjie Fan, Lu Sun, Xiurui Han, Ruyue Fan, Maojun Zhang, Xiaomei Yan…
    Citation: Gut Pathogens 2021 13:39
  15. The urea breath test (UBT) is widely used for diagnosing Helicobacter pylori infection. In the Shenzhen Kuichong People’s Hospital, some UBT findings were contradictory to the histology outcomes, therefore this s...

    Authors: Xiangyu Wang, Shuzhen Zhang, Eng Guan Chua, Yongsheng He, Xiaofeng Li, Aijun Liu, Haiting Chen, Michael J. Wise, Barry J. Marshall, Dayong Sun, Xuehong Li and Chin Yen Tay
    Citation: Gut Pathogens 2021 13:38
  16. The classification of natural antimicrobials as potential antibiotic replacements is still hampered by the absence of clear biological mechanisms behind their mode of action. This study investigated the mechan...

    Authors: Igori Balta, Adela Marcu, Mark Linton, Carmel Kelly, Ozan Gundogdu, Lavinia Stef, Ioan Pet, Patrick Ward, Myriam Deshaies, Todd Callaway, Phittawat Sopharat, Gratiela Gradisteanu-Pircalabioru and Nicolae Corcionivoschi
    Citation: Gut Pathogens 2021 13:37
  17. Even though the incidence of H. pylori infection among Malays in the Malay Peninsula is low, we observed a high H. pylori prevalence in Sumatra, which is the main residence of Indonesian Malays. H. pylori prevale...

    Authors: Ari Fahrial Syam, Langgeng Agung Waskito, Yudith Annisa Ayu Rezkitha, Rentha Monica Simamora, Fauzi Yusuf, Kanserina Esthera Danchi, Ahmad Fuad Bakry, Arnelis, Erwin Mulya, Gontar Alamsyah Siregar, Titong Sugihartono, Hasan Maulahela, Dalla Doohan, Muhammad Miftahussurur and Yoshio Yamaoka
    Citation: Gut Pathogens 2021 13:36
  18. Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, including non-typhoidal salmonellosis, wh...

    Authors: Sohyun Lee, Nanjoo Park, Sujung Yun, Eunseon Hur, Jiwon Song, Hanna Lee, Yongsug Kim and Sangryeol Ryu
    Citation: Gut Pathogens 2021 13:35
  19. Norovirus genotype GII.3[P12] strains have been an important pathogen for sporadic gastroenteritis infection. In previous studies of GII.3[P12], the number of specimens and time span are relatively small, whic...

    Authors: Jianguang Fu, Jing Ai, Changjun Bao, Jun Zhang, Qingbin Wu, Liguo Zhu, Jianli Hu and Zheng Xing
    Citation: Gut Pathogens 2021 13:34
  20. Diarrhea remains the leading cause of childhood illness in China. Better understanding of burden and etiology of diarrheal diseases is important for development of effective prevention measures.

    Authors: Hong-Lu Zhou, Theresa Bessey, Song-Mei Wang, Zhao-Jun Mo, Leslie Barclay, Jin-Xia Wang, Can-Jing Zhang, Jing-Chen Ma, Chao Qiu, Gan Zhao, Rong-Cheng Li, Yu-Liang Zhao, Baoming Jiang and Xuan-Yi Wang
    Citation: Gut Pathogens 2021 13:33
  21. Although Escherichia coli is the most frequently isolated microorganism in acute biliary tract infections with bacteremia, data regarding its virulence are limited.

    Authors: Mahoko Ikeda, Tatsuya Kobayashi, Fumie Fujimoto, Yuta Okada, Yoshimi Higurashi, Keita Tatsuno, Shu Okugawa and Kyoji Moriya
    Citation: Gut Pathogens 2021 13:32
  22. Mycobacterium avium subspecies paratuberculosis (MAP), the cause of Johne disease, is a slow growing mycobacterium. Viable MAP detection is difficult, inconstant and time-consuming. The purpose of this study was ...

    Authors: Robert J. Greenstein, Liya Su, Irene R. Grant, Antonio C. G. Foddai, Amy Turner, Jason S. Nagati, Sheldon T. Brown and Judith R. Stabel
    Citation: Gut Pathogens 2021 13:30
  23. By 27 June 2020, almost half a million people had died due to COVID-19 infections. The susceptibility and severity of infection vary significantly across nations. The contribution of chronic viral and parasiti...

    Authors: Enas Fakhry Abdel-Hamed, Mohamed N. Ibrahim, Nahed E. Mostafa, Howayda S. F. Moawad, Nahla E. Elgammal, Ehab M. Darwiesh, Dina S. El-rafey, Nissreen E. ElBadawy, Emad Ali Al-Khoufi and Salwa I. Hindawi
    Citation: Gut Pathogens 2021 13:29
  24. Poor self-care skills and personal hygiene resulted from limitations in learning and understanding, put intellectually disabled individuals at greater risk for intestinal parasitic infections (IPIs). Despite s...

    Authors: Mohammad Javad Abbaszadeh Afshar, Mehdi Mohebali, Sina Mohtasebi, Aref Teimouri, Bahareh Sedaghat and Reza Saberi
    Citation: Gut Pathogens 2021 13:28
  25. Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is an important zoonotic agent worldwide. The aim of this work was to compare genetically 117 S. Typhimurium isolated from different source...

    Authors: Amanda Ap. Seribelli, Patrick da Silva, Marcelo Ferreira da Cruz, Fernanda de Almeida, Miliane R. Frazão, Marta I. C. Medeiros, Dália dos P. Rodrigues, Jalusa D. Kich, Leandro de Jesus Benevides, Siomar de C. Soares, Marc W. Allard and Juliana Pfrimer. Falcão
    Citation: Gut Pathogens 2021 13:27
  26. Helicobacter cinaedi are motile, gram-negative spiral rods with a natural reservoir in the intestinal tract of hamsters and rhesus monkeys. In humans, H. cinaedi has been reported in different human infections li...

    Authors: Sofie Larsen Rasmussen, Iben Ørsted, Irene Harder Tarpgaard and Hans Linde Nielsen
    Citation: Gut Pathogens 2021 13:26
  27. Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer's disease (AD) worldwide. The prevalence of small intestinal bacterial overgrowth (SIBO) in PD patients is high. ...

    Authors: Xiaoqing Li, Xin Feng, Zhongxiang Jiang and Zheng Jiang
    Citation: Gut Pathogens 2021 13:25
  28. Cytomegalovirus (CMV)-associated gastrointestinal diseases usually occur in immunocompromised patients; however, few cases has also been described in healthy hosts despite still unclear pathological mechanisms...

    Authors: Daisuke Murakami, Hideaki Harada, Masayuki Yamato and Yuji Amano
    Citation: Gut Pathogens 2021 13:24
  29. The cytotoxin-associated gene A (cagA) is one of the most important virulence factors of Helicobacter pylori (H. pylori). There is a highly polymorphic Glu-Pro-Ile-Tyr-Ala (EPIYA) repeat region in the C-terminal ...

    Authors: Zhijing Xue, Yuanhai You, Lihua He, Yanan Gong, Lu Sun, Xiurui Han, Ruyue Fan, Kangle Zhai, Yaming Yang, Maojun Zhang, Xiaomei Yan and Jianzhong Zhang
    Citation: Gut Pathogens 2021 13:23
  30. Interferon-alpha (IFN-α) and nucleot(s)ide analogs (NAs) are first-line drugs for the treatment of chronic hepatitis B virus (HBV) infections. Generally, NAs target the reverse transcription of HBV pregenomic ...

    Authors: Gang Wang, Jun Guan, Nazif U. Khan, Guojun Li, Junwei Shao, Qihui Zhou, Lichen Xu, Chunhong Huang, Jingwen Deng, Haihong Zhu and Zhi Chen
    Citation: Gut Pathogens 2021 13:22
  31. Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial...

    Authors: Muhammad U. Sohail, Hebah A. Al Khatib, Asmaa A. Al Thani, Khalid Al Ansari, Hadi M. Yassine and Maha Al-Asmakh
    Citation: Gut Pathogens 2021 13:21
  32. One of the approaches to cure human immunodeficiency virus (HIV) is the use of therapeutic vaccination. We have launched the Provir/Latitude 45 study to identify conserved CTL epitopes in archived HIV-1 DNA ac...

    Authors: Patricia Recordon-Pinson, Annie Gosselin, Petronela Ancuta, Jean-Pierre Routy and Hervé Fleury
    Citation: Gut Pathogens 2021 13:20
  33. Colorectal cancer (CRC) is one of the top ten causes of cancer deaths in the world. Despite an increased prevalence of colorectal cancer has been documented from developing countries, there is no any report re...

    Authors: Yesuf Adem Siraj, Melesse Gebeyehu Biadgelign, Mensur Osman Yassin and Yohannes Zenebe Chekol
    Citation: Gut Pathogens 2021 13:19
  34. Infections caused by multidrug-resistant shigellae resistant to broad-spectrum cephalosporins are becoming more prevalent in the Middle East. We report a case of severe diarrhea due to a multiresistant Shigella f...

    Authors: M. John Albert, Prashant Purohit, Laurent Poirel, Glen Carter and Dieter Bulach
    Citation: Gut Pathogens 2021 13:18
  35. Spontaneous bacterial peritonitis (SBP) is one of the most common infectious diseases in patients with cirrhosis and is associated with serious prognosis. A prevailing dogma posits that SBP is exacerbated by t...

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Abdul Rehman Zia Zaidi, Ali A. Rabaan, Alyaa Elhazmi and Awad Al-Omari
    Citation: Gut Pathogens 2021 13:17
  36. Alteration in the gut microbiota has been proposed in irritable bowel syndrome (IBS) pathogenesis, especially in the diarrheal type (IBS-D). We conducted this study to evaluate the fecal microbiota in Thai IBS...

    Authors: Sawangpong Jandee, Suppana Chuensakul and Suppasil Maneerat
    Citation: Gut Pathogens 2021 13:16
  37. The membrane fusion protein (mfp) gene locus of Vibrio parahaemolyticus consists of two operons, cpsQ-mfpABC and mfpABC, which are both required for biofilm formation. ToxR and CalR are required for the full viru...

    Authors: Yiquan Zhang, Yue Qiu, Xingfan Xue, Miaomiao Zhang, Junfang Sun, Xue Li, Lingfei Hu, Zhe Yin, Wenhui Yang, Renfei Lu and Dongsheng Zhou
    Citation: Gut Pathogens 2021 13:15
  38. COVID-19 is an acute respiratory distress syndrome and is often accompanied by gastrointestinal symptoms. The SARS-CoV-2 has been traced not only in nasopharyngeal and mid-nasal swabs but also in stool and rec...

    Authors: Jyoti Chhibber-Goel, Sreehari Gopinathan and Amit Sharma
    Citation: Gut Pathogens 2021 13:14
  39. This study aims to characterize, the gut and oral microbiome in Asian subjects with Crohn’s disease (CD) using whole genome shotgun sequencing, thereby allowing for strain-level comparison.

    Authors: Shijia Hu, Eileen Png, Michelle Gowans, David E. H. Ong, Paola Florez de Sessions, Jie Song and Niranjan Nagarajan
    Citation: Gut Pathogens 2021 13:13
  40. The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The do...

    Authors: Jolanta Gruszecka and Rafał Filip
    Citation: Gut Pathogens 2021 13:12
  41. Gastric adenocarcinoma is associated with H. pylori infection and inflammation that can result in the dysbiosis of gastric microbiota. The association of intestinal microbiota with gastric adenocarcinoma subtypes...

    Authors: Virinder Sarhadi, Binu Mathew, Arto Kokkola, Tiina Karla, Milja Tikkanen, Hilpi Rautelin, Leo Lahti, Pauli Puolakkainen and Sakari Knuutila
    Citation: Gut Pathogens 2021 13:11
  42. Clostridioides difficile infection (CDI) is a common hospital-associated diarrhea. Several antibiotics commonly associate with CDI; however, limited data are available on the duration of exposure prior to CDI. Mo...

    Authors: Khadijah M. Alammari and Abrar K. Thabit
    Citation: Gut Pathogens 2021 13:10
  43. Shewanella xiamenensis has been reported in water environment and in patients and can act as the originator of oxacillinase in gram-negative bacteria. In order to assess genome plasticity and its functional prope...

    Authors: Thongpan Leangapichart, Linda Hadjadj, Philippe Gautret and Jean-Marc Rolain
    Citation: Gut Pathogens 2021 13:9
  44. Shiga toxin-producing Escherichia coli (STEC) is a pathotype of E. coli that causes enteric and systemic diseases ranging from diarrhoea to severe hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The...

    Authors: Walid Elmonir, Samar Shalaan, Amin Tahoun, Samy F. Mahmoud, Etab M. Abo Remela, Radwa Eissa, Hanem El-Sharkawy, Mustafa Shukry and Rasha N. Zahran
    Citation: Gut Pathogens 2021 13:8
  45. SARS-CoV-2 has been detected not only in respiratory secretions, but also in stool collections. Here were sought to identify SARS-CoV-2 by enrichment next-generation sequencing (NGS) from fecal samples, and to...

    Authors: Andreas Papoutsis, Thomas Borody, Siba Dolai, Jordan Daniels, Skylar Steinberg, Brad Barrows and Sabine Hazan
    Citation: Gut Pathogens 2021 13:7
  46. Bacillus cereus is ubiquitous in nature, found in environments such as soil, plants, air, and part of the insect and human gut microbiome. The ability to produce endospores and biofilms contribute to their pathog...

    Authors: Balakrishnan N. V. Premkrishnan, Cassie E. Heinle, Akira Uchida, Rikky W. Purbojati, Kavita K. Kushwaha, Alexander Putra, Puramadathil Sasi Santhi, Benjamin W. Y. Khoo, Anthony Wong, Vineeth Kodengil Vettath, Daniela I. Drautz-Moses, Ana Carolina M. Junqueira and Stephan C. Schuster
    Citation: Gut Pathogens 2021 13:6
  47. Intestinal fibrosis is a frequent complication of Crohn’s disease. However, the factors that cause chronicity and promote fibrogenesis are not yet understood.

    Authors: Dina Chokr, Marjorie Cornu, Christel Neut, Clovis Bortolus, Rogatien Charlet, Pierre Desreumaux, Silvia Speca and Boualem Sendid
    Citation: Gut Pathogens 2021 13:5