Clostridium difficile is an anaerobic Gram-positive spore-forming gut pathogen that causes antibiotic-associated diarrhea worldwide. A small number of C. difficile strains express the ...
Authors: Zhong Peng, Sidi Liu, Xiujuan Meng, Wan Liang, Zhuofei Xu, Biao Tang, Yuanguo Wang, Juping Duan, Chenchao Fu, Bin Wu, Anhua Wu and Chunhui Li
Dysbiosis is linked to the cause of several human diseases, many of which having an immunity related component. This work investigated whether mice genetically selected for low or high antibody production disp...
Authors: Ana Carolina da Silva Santos, José Ricardo Jensen, Silvio Luis de Oliveira and Josias Rodrigues
Members of the genus Hafnia have been isolated from the feces of mammals, birds, reptiles, and fish, as well as from soil, water, sewage, and foods. Hafnia alvei is an opportunistic pathogen that has been implica...
Authors: Hye Seon Song, Joon Yong Kim, Yeon Bee Kim, Myeong Seon Jeong, Jisu Kang, Jin-Kyu Rhee, Joseph Kwon, Ju Suk Kim, Jong-Soon Choi, Hak-Jong Choi, Young-Do Nam and Seong Woon Roh
The serine protease HtrA is an important factor for regulating stress responses and protein quality control in bacteria. In recent studies, we have demonstrated that the gastric pathogen Helicobacter pylori can s...
Authors: Aileen Harrer, Manja Boehm, Steffen Backert and Nicole Tegtmeyer
Unrelated spore-forming bacteria share unique characteristics stemming from the presence of highly resistant endospores, leading to similar challenges in health and disease. These characteristics are related t...
Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen associated with community-acquired infections and nosocomial infections. From 2010 to 2015, K. pneumoniae testing was...
Authors: Bing Lu, Haijian Zhou, Xin Zhang, Mei Qu, Ying Huang and Quanyi Wang
Campylobacter is a well-known bacterial pathogen for triggering acute gastroenteritis in humans both in developed and developing countries. This organism is highly resistant to fluoroq...
Authors: Piyali Mukherjee, Shanta Dutta and Asish K. Mukhopadhyay
The pH of the human gastric mucosa varies around 2.5 so that only bacteria with strong acidic stress tolerance can colonize it. The ulcer causing Helicobacter pylori thrives in the gastric mucosa. We analyse the ...
Authors: Hilde S. Vollan, Tone Tannæs, Dominique A. Caugant, Gert Vriend and Geir Bukholm
Recent studies show that some Escherichia coli strains possessing a gene cluster named the pks island might have a causative role in the development of human colorectal cancer (CRC). In several reports from Europ...
Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease in ruminants and is associated with Crohn’s disease (CD) in humans, although the latter ...
Authors: Nicole Parrish, Aravinda Vadlamudi and Neil Goldberg
Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2) are essentially involved in ...
Authors: Stefan Bereswill, Ursula Grundmann, Marie E. Alutis, André Fischer, Anja A. Kühl and Markus M. Heimesaat
Clostridium perfringens is an opportunistic human pathogen that causes necrotic enteritis, mild diarrhea, clostridial myonecrosis or gas gangrene, sepsis, etc. In this study, we aim to...
Authors: Yeon Bee Kim, Joon Yong Kim, Hye Seon Song, Changsu Lee, Joseph Kwon, Jisu Kang, Jin-Kyu Rhee, Myeong Seon Jeong, Young-Do Nam and Seong Woon Roh
Vibrio campbellii is widely distributed in the marine environment and is an important pathogen of aquatic organisms such as shrimp, fish, and mollusks. An isolate of V. campbellii carr...
Authors: Xuan Dong, Hailiang Wang, Peizhuo Zou, Jiayuan Chen, Zhen Liu, Xuepeng Wang and Jie Huang
Shiga toxin (Stx) producing Escherichia coli (E. coli) (STEC) is the most frequent cause of diarrhoea-positive haemolytic uraemic syndrome (D + HUS) in humans. In 2011, a huge outbreak with an STEC O104:H4 strain...
Authors: Bettina Wöchtl, Florian Gunzer, Wilhelm Gerner, Hagen Gasse, Michaela Koch, Zoltán Bagó, Martin Ganter, Herbert Weissenböck, Nora Dinhopl, Sina M. Coldewey, Alexandra von Altrock, Karl-Heinz Waldmann, Armin Saalmüller, Kurt Zimmermann, Jörg Steinmann, Jan Kehrmann…
Bacillus cereus is well known as a gastrointestinal pathogen that causes food-borne illness. In the present study, we sequenced the complete genome of B. cereus FORC_013 isolated from ...
Authors: Hyun-Jin Koo, Sojin Ahn, Han Young Chung, Suyeon Kim, Kwondo Kim, Sangryeol Ryu, Ju-Hoon Lee, Sang Ho Choi and Heebal Kim
There is a growing concern about the increase in human morbidity and mortality caused by foodborne pathogens. Antibiotics were and still are used as the first line of defense against these pathogens, but an in...
Authors: Moloko Gloria Mathipa and Mapitsi Silvester Thantsha
Coeliac disease is an autoimmune disorder resulting from an interaction between diet, genome and immunity. The treatment of CoeD is lifelong adherence to a gluten free diet, which is associated with clinical a...
Authors: Joanna Harnett, Stephen P. Myers and Margaret Rolfe
Bifidobacterium longum 105-A produces markedly high amounts of capsular polysaccharides (CPS) and exopolysaccharides (EPS) that should play distinct roles in bacterial–host interaction...
Authors: Amin Tahoun, Hisayoshi Masutani, Hanem El-Sharkawy, Trudi Gillespie, Ryo P. Honda, Kazuo Kuwata, Mizuho Inagaki, Tomio Yabe, Izumi Nomura and Tohru Suzuki
In 2007, a nationwide Salmonella Tennessee outbreak occurred via contaminated peanut butter. Here, we developed a single-nucleotide polymorphism (SNP)-typing method for S. Tennessee to determine the clonal subtyp...
Authors: Hee-Jin Dong, Seongbeom Cho, David Boxrud, Shelly Rankin, Francis Downe, Judith Lovchik, Jim Gibson, Matt Erdman and A. Mahdi Saeed
Ruminants serve as one of the most important reservoirs for pathogenic Escherichia coli. Infection with E. coli, a foodborne enteropathogen, can lead to asymptomatic infections that can cause life-threatening com...
Authors: Mujeeb Ur Rehman, Hui Zhang, Muhammad Kashif Iqbal, Khalid Mehmood, Shucheng Huang, Fazul Nabi, Houqiang Luo, Yanfang Lan and Jiakui Li
Rotavirus (RV) induces diarrhoea through a sequence of enterotoxic and cytotoxic effects. The former are NSP4-dependent, induce calcium-dependent chloride secretion and involve oxidative stress. Diosmectite (D...
Authors: Vittoria Buccigrossi, Carla Russo, Amedeo Guarino, Maiara Brusco de Freitas and Alfredo Guarino
Helicobacter pylori infection is associated with risk for chronic gastritis (CG), gastric ulcer (GU), duodenal ulcer (DU), and gastric cancer (GC). The H. pylori Cag type IV secretion ...
Authors: Hirofumi Ogawa, Akira Iwamoto, Toshihito Tanahashi, Rina Okada, Koji Yamamoto, Shin Nishiumi, Masaru Yoshida and Takeshi Azuma
As a primary source of Shiga-toxin-producing Escherichia coli (STEC) infection, cattle are often targeted to develop strategies for reducing STEC contamination. Monitoring the virulence potentials of STEC isolate...
Authors: Hee-Jin Dong, Soomin Lee, Woohyun Kim, Jae-Uk An, Junhyung Kim, Danil Kim and Seongbeom Cho
Enterococcus faecalis, generally considered as a saprophytic bowel commensal, has recently emerged as an important nosocomial pathogen causing severe urinary tract infections, surgical...
Authors: Kelly Biaggini, Valérie Borrel, Sabine Szunerits, Rabah Boukherroub, Awa N’Diaye, Arthur Zébré, Maryse Bonnin-Jusserand, Guillaume Duflos, Marc Feuilloley, Djamel Drider, Pierre Déchelotte and Nathalie Connil
The gut of human harbors diverse commensal microbiota performing an array of beneficial role for the hosts. In the present study, the major commensal gut bacteria isolated by culturing methods from 15 children...
Authors: Shirajum Monira, Syeda Antara Shabnam, Sk. Imran Ali, Abdus Sadique, Fatema-Tuz Johura, Kazi Zillur Rahman, Nur Haque Alam, Haruo Watanabe and Munirul Alam
